Protein Alignment tup and isl1b

DIOPT Version :9

• Sequence 1: NP_001286068.1
• Gene: tup / 35147
• FlyBaseID: FBgn0003896
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001002043.1
• Gene: isl1b / 415131
• ZFINID: ZDB-GENE-040624-1
• Length: 323
• Species: Danio rerio
• Alignment Length: 356
• Identity: 152/356 - (42%)
• Similarity: 200/356 - (56%)
• Gaps: 75/356 - (21%)

  Fly    52 SHCVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRLFGTKC 116
            |.|||||.:|.|::|:||:|||||||.||||.||.||||||||||:|||||:|:..|.||..:||
Zfish    17 SFCVGCGLEILDRFIVRVSPDLEWHARCLKCAECHQFLDESCTCFIRDGKTFCREHYSRLSTSKC 81

  Fly   117 DKCGNSFSKNDFVMRAKTKIFHIECFRCSACARQLLPGDEFALRDAGALYCKEDHDVLEKSSQSS 181
            .||..:|...:||||::..|:|::||||..|.|.||.|||:.|:| |.|.|.:.|        :.
Zfish    82 AKCDKAFISKEFVMRSQVNIYHVQCFRCEGCNRPLLSGDEYVLQD-GQLLCTDHH--------NK 137

  Fly   182 LTSSSVESNNNISSSNNNNTNLSNNNHSSELGSMSDSGSESGSHKSIRDKRPSGPSDGKPTRVRT 246
            |.|:|:                   |...|.|..|:....:.|..|::.:      ..:.|||||
Zfish   138 LMSASI-------------------NQQKEAGDPSEEIKSTLSWSSMQRR------SERATRVRT 177

  Fly   247 VLNEKQLHTLRTCYNANPRPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEK 311
            ||:|.||..|:|||.|||||||||||||||||.|||||||||||||||||||:::.|: ..|::.
Zfish   178 VLSETQLCMLQTCYTANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSLTMR-HTQKQL 241

  Fly   312 EGRKLGYGAMQGIPMIASSPVRHDSPLNLQGLDVQTYQPPWKALSDFALHADLDSNGAINTHTPA 376
            ||.     .:...|::..|....||.:.:        .||||.|:||.|..:.:..        :
Zfish   242 EGH-----LVSEEPLLLVSTESQDSDVMI--------SPPWKLLTDFILQNEAEHR--------S 285

  Fly   377 FQQLVNQMHGYDLNGMPILPPHPHSHPAQGP 407
            |.|::                   |.|.:||
Zfish   286 FPQML-------------------SLPTEGP 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tup	NP_001286068.1	LIM1_Isl	54..108	CDD:188752	39/53 (74%)
		LIM2_Isl	116..171	CDD:188760	26/54 (48%)
		HOX	241..297	CDD:197696	47/55 (85%)
isl1b	NP_001002043.1	LIM1_Isl	19..73	CDD:188752	39/53 (74%)
		LIM	81..135	CDD:295319	26/54 (48%)
		HOX	174..228	CDD:197696	46/53 (87%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BAXJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45829
OrthoDB	1	1.010	-	-		D403874at33208
OrthoFinder	1	1.000	-	-		FOG0002096
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24204
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1777
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.890