Protein Alignment tup and Scr

DIOPT Version :10

• Sequence 1: NP_476775.1
• Gene: tup / 35147
• FlyBaseID: FBgn0003896
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 469
• Identity: 84/469 - (17%)
• Similarity: 137/469 - (29%)
• Gaps: 198/469 - (42%)

  Fly   148 ARQLLPGDEFALRDAGALYCKEDHDVLEKSSQSSLTSSSVESNNNISSSNNNNT-------NLS- 204
            |:|..|..:...:.|. :.||..:|.:..........|...:|||.::|||||:       :||
  Fly   149 AQQQHPQQQQQQQQAN-ISCKYANDPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLST 212

  Fly   205 --------------------------------------NNNHS--------------------SE 211
                                                  |||||                    .:
  Fly   213 RDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGD 277

  Fly   212 LGSMSDSGSESGSHKSIRDKRPSGP-----------------SDGKPTRVRTVLNEKQLHTLRTC 259
            ..|.||||:|:||.::..:.:.:.|                 ::|:..|.||.....|...|...
  Fly   278 SDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKE 342

  Fly   260 YNANPRPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEKEGRKLGYGAMQGI 324
            ::.|.......:.::.....|:.|.|::||||:|.|.||:
  Fly   343 FHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE------------------------- 382

  Fly   325 PMIASSPVRHDSPLNLQGLDVQTYQPPWKALSDFALHADLDSNGAINTHTPAFQQLVNQMHGYDL 389
                                                                          :.:
  Fly   383 --------------------------------------------------------------HKM 385

  Fly   390 NGMPILPPHPHSHPAQGPPHQHPPPPGGPHNHQNQQPNQQPGGSSLDSGITSHHHPDSTDSYVTY 454
            ..|.|:|             .|..|.|.|::..:..|:|....|:.|:     .|...|...:..
  Fly   386 ASMNIVP-------------YHMGPYGHPYHQFDIHPSQFAHLSAXDA-----WHFSGTGXRLNQ 432

  Fly   455 LESDDKSKLALTPSSSSSASAGTSISSPPSGVGAGGGGAVGGGSGVLGLGVVANQSATEQLMQML 519
            |..:..       .::::|||.:...|...|...||...||||:|  |.|.:||..:.......|
  Fly   433 LYQEPY-------QTAAAASAASGYQSQDGGPIGGGSVGVGGGAG--GPGSLANGGSNGSGPNSL 488

  Fly   520 QKVTGSASPASHAV 533
            .....|:|.|...:
  Fly   489 FASAASSSQAPDCI 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tup	NP_476775.1	LIM1_Isl	54..108	CDD:188752
		LIM2_Isl	116..171	CDD:188760	6/22 (27%)
		HOX	241..297	CDD:197696	15/55 (27%)
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	15/55 (27%)