Protein Alignment tup and ap

DIOPT Version :10

• Sequence 1: NP_476775.1
• Gene: tup / 35147
• FlyBaseID: FBgn0003896
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_724428.1
• Gene: ap / 35509
• FlyBaseID: FBgn0267978
• Length: 469
• Species: Drosophila melanogaster
• Alignment Length: 337
• Identity: 105/337 - (31%)
• Similarity: 158/337 - (46%)
• Gaps: 56/337 - (16%)

  Fly    49 QRLSHCVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRLFG 113
            :.|..|.|||.||.|::.|. |.:..|||:||:|..|||.|:...:|:.|||..|||.||...||
  Fly   143 RNLDDCSGCGRQIQDRFYLS-AVEKRWHASCLQCYACRQPLERESSCYSRDGNIYCKNDYYSFFG 206

  Fly   114 T-KCDKCGNSFSKNDFVMRAKTKIFHIECFRCSACARQLLPGDEFALRDAGALYCKEDHDVLEKS 177
            | :|.:|..|.|.|:.||||:..:||:.||.|:.|...|..||::.:.|| .:||:..:.:   :
  Fly   207 TRRCSRCLASISSNELVMRARNLVFHVNCFCCTVCHTPLTKGDQYGIIDA-LIYCRTHYSI---A 267

  Fly   178 SQSSLTSSSVESNNNISSSNNNNTNLSNNNHSSELGSMSDSG-------SESGSHKSIRDK---R 232
            .:....|||:.:....|:...:..|.|::.||....|:..:|       ..:|..:..|.|   |
  Fly   268 REGDTASSSMSATYPYSAQFGSPHNDSSSPHSDPSRSIVPTGIFVPASHVINGLPQPARQKGRPR 332

  Fly   233 PSGPSD--------------------------GKPTRVRTVLNEKQLHTLRTCYNANPRPDALMK 271
            ...|.|                          .:..|:||.....||.|:::.:..|..|||...
  Fly   333 KRKPKDIEAFTANIDLNTEYVDFGRGSHLSSSSRTKRMRTSFKHHQLRTMKSYFAINHNPDAKDL 397

  Fly   272 EQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEKEG-RKLGYGAMQGIPMIASSPV--- 332
            :||.:.|.|..||::|||||.|.|.:      ::.|:|:..| .:.|.||:....:...||.
  Fly   398 KQLSQKTGLPKRVLQVWFQNARAKWR------RMMMKQDGSGLLEKGEGALDLDSISVHSPTSFI 456

  Fly   333 ----RHDSPLNL 340
                ....||||
  Fly   457 LGGPNSTPPLNL 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tup	NP_476775.1	LIM1_Isl	54..108	CDD:188752	26/53 (49%)
		LIM2_Isl	116..171	CDD:188760	22/54 (41%)
		HOX	241..297	CDD:197696	23/55 (42%)
ap	NP_724428.1	LIM1_Lhx2_Lhx9	148..201	CDD:188755	26/53 (49%)
		LIM2_Lhx2_Lhx9	206..264	CDD:188763	24/58 (41%)
		Homeodomain	368..424	CDD:459649	23/61 (38%)