Protein Alignment tup and ceh-14

DIOPT Version :10

• Sequence 1: NP_476775.1
• Gene: tup / 35147
• FlyBaseID: FBgn0003896
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_509273.1
• Gene: ceh-14 / 181012
• WormBaseID: WBGene00000438
• Length: 351
• Species: Caenorhabditis elegans
• Alignment Length: 373
• Identity: 91/373 - (24%)
• Similarity: 145/373 - (38%)
• Gaps: 116/373 - (31%)

  Fly    54 CVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRLFGTKCDK 118
            |..|..:|.|:::.:|.... :|::||:|..|:..|  ..|||:|:...||:..:.:.|||||..
 Worm    48 CSLCDKKIRDRFVSKVNGRC-YHSSCLRCSTCKDEL--GATCFLREDSMYCRAHFYKKFGTKCSS 109

  Fly   119 CGNSFSKNDFVMRAKTKIFHIECFRCSACARQLLPGDEFAL-RDAGALYCKEDHDVLEKSSQSSL 182
            |......:..|.:|...::|:|||:|..|.|.|..|:||.| .|...|.||:|::
 Worm   110 CNEGIVPDHVVRKASNHVYHVECFQCFICKRSLETGEEFYLIADDARLVCKDDYE---------- 164

  Fly   183 TSSSVESNNNISSSNNNNTNLSNNNHSSELGSMSDSGSESGSHKSIRDKRPSGPSDGKPTRVRTV 247
                                .:.:.|.:||                       ..||...|.||.
 Worm   165 --------------------QARDKHCNEL-----------------------EGDGSNKRPRTT 186

  Fly   248 LNEKQLHTLRTCYNANPRPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEKE 312
            ::.|.|.||:..|..:.:|...::|||...|.|..||::|||||:|.|:|:         .::..
 Worm   187 ISAKSLETLKQAYQTSSKPARHVREQLASETGLDMRVVQVWFQNRRAKEKR---------LKKDA 242

  Fly   313 GRKLGYGAMQGIPMIASSPVRHDSPLNLQGLDVQTYQPPWKALSDFALHADLDSNG---AINTHT 374
            ||:                                    ||:.:    .|:.|||.   :||..:
 Worm   243 GRR------------------------------------WKSSN----RAESDSNSPIESINGQS 267

  Fly   375 PAFQQLVNQM-----HGYDLNGMPILPP--HPHSHPAQGPPHQHPPPP 415
            |.:..|.:.|     ..|..:.....|.  :.:..|:..||..|...|
 Worm   268 PNYLYLDHPMDDGNESNYLFHSREQTPDKYYRNETPSTDPPPMHMTTP 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tup	NP_476775.1	LIM1_Isl	54..108	CDD:188752	17/53 (32%)
		LIM2_Isl	116..171	CDD:188760	20/55 (36%)
		HOX	241..297	CDD:197696	23/55 (42%)
ceh-14	NP_509273.1	LIM	48..103	CDD:395333	17/57 (30%)
		LIM2_Lhx3_Lhx4	107..163	CDD:188762	20/55 (36%)
		COG5576	<172..295	CDD:227863	42/194 (22%)
		Homeodomain	181..237	CDD:459649	23/55 (42%)