Protein Alignment tup and lim-6

DIOPT Version :10

• Sequence 1: NP_476775.1
• Gene: tup / 35147
• FlyBaseID: FBgn0003896
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001256980.1
• Gene: lim-6 / 180459
• WormBaseID: WBGene00002988
• Length: 316
• Species: Caenorhabditis elegans
• Alignment Length: 351
• Identity: 98/351 - (27%)
• Similarity: 144/351 - (41%)
• Gaps: 79/351 - (22%)

  Fly    54 CVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRLFGTKCDK 118
            |.|||..|.|:||.||..| .:|.:||:|..|:..|.....||.|.|..||:.|:..|:|.:|.:
 Worm    42 CSGCGCLIKDRYIYRVMED-SYHESCLRCSCCQLSLSSFKKCFSRHGNIYCEHDHQMLYGKRCRR 105

  Fly   119 CGNSFSKNDFVMRAKTKIFHIECFRCSACARQLLPGDEFALRDAGALYCKEDHDVLEKSSQSSLT 183
            |.......|.|.|.....:|.:||.|.:|.|....|||:.:.| |.::|:.|:
 Worm   106 CMTLLLPTDIVHRVHFMYYHAQCFSCCSCQRPFNLGDEYHVFD-GEVFCRNDY------------ 157

  Fly   184 SSSVESNNNISSSNNNNTNLSNNNHSSELGSMSDSGSESGSHKSIRDKRPSGPSDGKPTRVRTVL 248
                       .|..|...:||          .|...|......|..|.|..|        ||:|
 Worm   158 -----------QSICNFQTISN----------PDPLMEEVVRSEIHRKTPKRP--------RTIL 193

  Fly   249 NEKQLHTLRTCYNANPRPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEKEG 313
            |.:|....:|.:..:.:|...::|||...|.||.||::|||||:|.|.|      ||..:....|
 Worm   194 NAQQRRQFKTAFERSSKPSRKVREQLANETGLSVRVVQVWFQNQRAKIK------KLNKKDSDSG 252

  Fly   314 RKLGYG-AMQG--IPMIASSPVRHDSPLNLQGLDVQTYQPPWKALSDFALHADLDSNGAINTHTP 375
            ....:| ..:|  ...|.||....:|.:||...:|:|.:                    .:::|.
 Worm   253 DTFKHGPGSEGRSTEDIRSSDDEEESVINLDADEVETSE--------------------TSSYTD 297

  Fly   376 AFQQLVNQMHGYDLNGMPILPPHPHS 401
            ..|:|      |::....|..|: ||
 Worm   298 PIQKL------YNMTSSQIYFPY-HS 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tup	NP_476775.1	LIM1_Isl	54..108	CDD:188752	23/53 (43%)
		LIM2_Isl	116..171	CDD:188760	17/54 (31%)
		HOX	241..297	CDD:197696	22/55 (40%)
lim-6	NP_001256980.1	LIM	42..95	CDD:413332	23/53 (43%)
		LIM	101..157	CDD:413332	17/56 (30%)
		Homeodomain	187..243	CDD:459649	24/69 (35%)