Protein Alignment tup and Lim1

DIOPT Version :10

• Sequence 1: NP_476775.1
• Gene: tup / 35147
• FlyBaseID: FBgn0003896
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_309513.4
• Gene: Lim1 / 1270792
• VectorBaseID: AGAMI1_014571
• Length: 500
• Species: Anopheles gambiae
• Alignment Length: 523
• Identity: 140/523 - (26%)
• Similarity: 194/523 - (37%)
• Gaps: 169/523 - (32%)

  Fly    54 CVGCGGQIHDQYILRVAPDLE--WHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRLFGTKC 116
            |.||...|.|:::|.|   ||  |||.|::|.||.|.|.:.  ||.|:.|.||:.|:.|.:||||
Mosquito    27 CAGCNKPILDKFLLNV---LERGWHATCVRCCECHQPLADK--CFSRESKLYCRNDFFRRYGTKC 86

  Fly   117 DKCGNSFSKNDFVMRAKTKIFHIECFRCSACARQLLPGDEFALRDAGALYCKEDHDVLEKSSQ-- 179
            ..||...:.:|.|.:.:.|:||:.||.|..|.:|:..|::..:.|.....||:|: :|.|...
Mosquito    87 SGCGQGIAPSDLVRKPRDKVFHLNCFTCCICRKQISTGEQLYVLDDNKFICKDDY-ILGKGPHPM 150

  Fly   180 -SSLTSSSVESNNN------------IS--------------------SSNNNNTNLSNNNHSSE 211
             .||..|:.|..:.            :|                    |..:.:|:....:..|:
Mosquito   151 TDSLMGSASEDEDEEDQMRPGVLAGLVSGGAGAAGLHHGDGPLGASDLSVQSMSTDSKTGHDDSD 215

  Fly   212 LGSMSDSGSESGSHKSIRDKRPSGPSDGKPTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVE 276
            .||: |...:........:|.|...:..|....||.:..|||..|:..::..|:|...::|||.:
Mosquito   216 QGSL-DGDPDCRGDSQAENKSPDDGAGSKRRGPRTTIKAKQLEVLKNAFSQTPKPTRHIREQLAK 279

  Fly   277 MTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEKEGRKLGYGAMQGIPMIASSPVRHDSPLNLQ 341
            .|.|..|||:|||||||.|:::.           |:...:|.|     |....:......|:||.
Mosquito   280 ETGLPMRVIQVWFQNKRSKERRL-----------KQLTSMGRG-----PFFGGARKMRGFPMNLS 328

  Fly   342 --GLDVQTYQPPWKALSDFALHADLDSNGAINTHTPAFQQLVNQMHGYDLNGMPILPPHPH---- 400
              |||...:  |:     ||.....|                   .||   |.|  |.|||
Mosquito   329 PGGLDEPGF--PY-----FAADGKFD-------------------FGY---GGP--PFHPHDAPF 362

  Fly   401 --SHPAQGP--------PHQHPPP--------------------PGGPHNHQNQQPNQQP----G 431
              .||..||        |..||.|                    ||||..     |...|    |
Mosquito   363 FGGHPGAGPMPFGGPGGPMDHPIPMVGDFGMAGPDGGPGGMLGGPGGPGG-----PGGGPGGFMG 422

  Fly   432 GSSLDSGITSHHHPDSTDSYVTYLESDDKSKLALTPSSSSSASAGTSISSPPSGVGAGGGGAVGG 496
            |.....|....|.||....                                 .|||.||||..||
Mosquito   423 GPGGPGGPQQGHGPDGMMG---------------------------------GGVGGGGGGGGGG 454

  Fly   497 GSG 499
            |.|
Mosquito   455 GGG 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tup	NP_476775.1	LIM1_Isl	54..108	CDD:188752	24/55 (44%)
		LIM2_Isl	116..171	CDD:188760	17/54 (31%)
		HOX	241..297	CDD:197696	24/55 (44%)
Lim1	XP_309513.4	None