Protein Alignment tup and isl2

DIOPT Version :9

• Sequence 1: NP_001286068.1
• Gene: tup / 35147
• FlyBaseID: FBgn0003896
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001159513.1
• Gene: isl2 / 100306962
• XenbaseID: XB-GENE-487556
• Length: 333
• Species: Xenopus tropicalis
• Alignment Length: 364
• Identity: 191/364 - (52%)
• Similarity: 228/364 - (62%)
• Gaps: 67/364 - (18%)

  Fly    47 KKQRLSHCVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRL 111
            ||..|:.|||||..|.|||||||:||||||||||||.||.|:|||:||||||||||||||||:||
 Frog    20 KKAGLAVCVGCGSHILDQYILRVSPDLEWHAACLKCAECSQYLDENCTCFVRDGKTYCKRDYIRL 84

  Fly   112 FGTKCDKCGNSFSKNDFVMRAKTKIFHIECFRCSACARQLLPGDEFALRDAGALYCKEDHDVLEK 176
            |..:|.:|..:..:::.|||...:::|.:|||||.|:|:||||:|.:|||.. |.|..:|
 Frog    85 FSARCPRCQGTLPRSELVMRVGERVYHTDCFRCSVCSRRLLPGEEISLRDQD-LLCGAEH----- 143

  Fly   177 SSQSSLTSSSVESNNNISSSNNNNTNLSNNNHSSELGSMSDSGSESGSHKSIRDKRPSGPSDGKP 241
                                     |||::...|.|        .|..||...          |.
 Frog   144 -------------------------NLSDSGRPSSL--------RSHIHKQTE----------KT 165

  Fly   242 TRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQ 306
            |||||||||||||||||||.|||||||||||||||||.||||||||||||||||||||:|.|| |
 Frog   166 TRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMK-Q 229

  Fly   307 MQQEKEGRKLGYGAMQGIPMIASSPVRHDSPLNLQGLDVQTYQPPWKALSDFALHADLDSNGAIN 371
            :||::...|.....:.|.||:|.||:||||.:....::||||||||||||||||.:|||.
 Frog   230 LQQQQLNDKTSLQGLTGTPMVAGSPIRHDSAVQGSAVEVQTYQPPWKALSDFALQSDLDQ----- 289

  Fly   372 THTPAFQQLVN--------QMHGYDLNGMPI-LPPHPHS 401
               |||||||:        ...|.|:..:.. ||..|:|
 Frog   290 ---PAFQQLVSFSESGSLGNSSGSDIASLSSQLPDTPNS 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tup	NP_001286068.1	LIM1_Isl	54..108	CDD:188752	45/53 (85%)
		LIM2_Isl	116..171	CDD:188760	23/54 (43%)
		HOX	241..297	CDD:197696	52/55 (95%)
isl2	NP_001159513.1	LIM1_Isl	27..81	CDD:188752	45/53 (85%)
		LIM2_Isl	89..143	CDD:188760	23/54 (43%)
		HOX	165..221	CDD:197696	52/55 (95%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	124	1.000	Domainoid score	I5447
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	396	1.000	Inparanoid score	I1912
OMA	1	1.010	-	-		QHG45829
OrthoDB	1	1.010	-	-		D403874at33208
OrthoFinder	1	1.000	-	-		FOG0002096
OrthoInspector	1	1.000	-	-		otm49254
Panther	1	1.100	-	-	LDO	PTHR24204
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5473
SonicParanoid	1	1.000	-	-		X1777
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110