Protein Alignment CG10602 and AAP1

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_011913.1
• Gene: AAP1 / 856443
• SGDID: S000001089
• Length: 856
• Species: Saccharomyces cerevisiae
• Alignment Length: 575
• Identity: 141/575 - (24%)
• Similarity: 234/575 - (40%)
• Gaps: 107/575 - (18%)

  Fly    86 PDLITTEHSALNWKIDFAATKIQGSVLHRFKVLTANLDKILLDVRDINVTNATLLAGGSELPINF 150
            |:.:|..|..:..:.:|.|...:||:....::...:::.:.::..:|:..:|. :.|.:.:.:|
Yeast     7 PNNVTPLHYDITLEPNFRAFTFEGSLKIDLQINDHSINSVQINYLEIDFHSAR-IEGVNAIEVN- 69

  Fly   151 FISDAVDDIGQKLTLELPSGTAKG---SLNVRIDYE--TSSSASGLQWLNPTQTLGKEHPYM-FS 209
                 .::..||.||..|:||.:.   |..:.|.:.  .:...:|......|..:..|..|| .:
Yeast    70 -----KNENQQKATLVFPNGTFENLGPSAKLEIIFSGILNDQMAGFYRAKYTDKVTGETKYMATT 129

  Fly   210 QCQAIHARSVIPCQDTPAVKFTYDATVEHPSELTAL--MSALIDKKEPGK--TLFKQEVPIPAYL 270
            |.:|..||...||.|.|.:|.|:..|:...|.||.|  |....:..:.||  |.|.....:..||
Yeast   130 QMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVRNETIKEGKKYTTFNTTPKMSTYL 194

  Fly   271 VAIAIGKLVSRPLGENS--------SVWAEEAIVDACAEEFSETATMLKTATELCGPYVWKQYDL 327
            ||..:..|  |.:..|:        |...:|......|...:.|....:....:       :|.|
Yeast   195 VAFIVADL--RYVESNNFRIPVRVYSTPGDEKFGQFAANLAARTLRFFEDTFNI-------EYPL 250

  Fly   328 ----LVMPPSFPFGGMEN-PCLTF-VTPTLLAGDKS-------LADVVAHEIAHSWTGNLVTNKN 379
                :|....|..|.||| ..:|: |...||..:.|       :|:|:.||:||.|.|||||...
Yeast   251 PKMDMVAVHEFSAGAMENWGLVTYRVIDLLLDIENSSLDRIQRVAEVIQHELAHQWFGNLVTMDW 315

  Fly   380 FEHFWLNEGFTVFV---------------ESKIVGRMQGAKELDFKMLSNLTDLQECIRTQLNKT 429
            :|..||||||..::               |..:...:|.|..||....|:      .|...:|..
Yeast   316 WEGLWLNEGFATWMSWYSCNKFQPEWKVWEQYVTDNLQRALNLDSLRSSH------PIEVPVNNA 374

  Fly   430 PELTKLVVDLSNCGPDDAFSSVPYIKGSTFLRYLEDLFGGPTVFEPFLRDYLKKYAYKSIETKDF 494
            .|:.::            |.::.|.|||:.||.:....|..| |...:..||.|:.|.:.:|.|
Yeast   375 DEINQI------------FDAISYSKGSSLLRMISKWLGEET-FIKGVSQYLNKFKYGNAKTGD- 425

  Fly   495 QSALYDYFIDTDKKDKLSAVDWDLWLKSEGMPPVIPNFDESLANVTKELASLWSSKSVAELADSA 559
               |:|...|...||..|.:  ::|.|..|.|  :.:..|....:|.......|:..|.|..|:
Yeast   426 ---LWDALADASGKDVCSVM--NIWTKRVGFP--VLSVKEHKNKITLTQHRYLSTGDVKEEEDT- 482

  Fly   560 EIKTTISIHQLIDFLGKLIESKDIVDL-NEGKINLLESTYNLKSSKNAEVRFRLN 613
                  :|:.:      |:..||...: |...:|...:|:.||:    |..|::|
Yeast   483 ------TIYPI------LLALKDSTGIDNTLVLNEKSATFELKN----EEFFKIN 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856
		leuko_A4_hydro	79..681	CDD:274120	141/575 (25%)
AAP1	NP_011913.1	M1_APN-Q_like	13..447	CDD:341064	118/474 (25%)
		ERAP1_C	517..833	CDD:463368	2/5 (40%)