Protein Alignment CG10602 and LAP2

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_014353.1
• Gene: LAP2 / 855682
• SGDID: S000004990
• Length: 671
• Species: Saccharomyces cerevisiae
• Alignment Length: 696
• Identity: 249/696 - (35%)
• Similarity: 374/696 - (53%)
• Gaps: 95/696 - (13%)

  Fly    45 IYHPMISTRGL----------CTSHKLLPIYQVQKRNMGRLGVVDPSSYSQPDLITTEHSALNWK 99
            ||.|.:..|||          .|.||:||: .:::|...|....|.|:.|........|:.||..
Yeast    14 IYLPTLRFRGLLTVISRNIHISTPHKMLPL-SIEQRRPSRSPEYDQSTLSNYKDFAVLHTDLNLS 77

  Fly   100 IDFAATKIQGSVLHRFKVL--------TANLDKILLDVRDINVTNATLLAGGSELPINFFISDAV 156
            :.|..:.|.|||..:.|.|        ..:||...|||:::::       .||:  .:|.|....
Yeast    78 VSFEKSAISGSVTFQLKKLHEGKNKSDELHLDTSYLDVQEVHI-------DGSK--ADFQIEQRK 133

  Fly   157 DDIGQKLTLELPSGTAKGSLNVRIDYETSSSASGLQWLNPTQTLGKEHPYMFSQCQAIHARSVIP 221
            :.:|.:|.:.  :.:...:..:.|.:.|:...:.|||||..||.|.: ||:|||.:||||||:.|
Yeast   134 EPLGSRLVIN--NASCNDNFTLNIQFRTTDKCTALQWLNSKQTKGGK-PYVFSQLEAIHARSLFP 195

  Fly   222 CQDTPAVKFTYDATVEHPSELTALMSAL-ID--KKEPGKTLFKQEVPIPAYLVAIAIGKLVSRPL 283
            |.|||:||.|:.|::|.|  |..:.|.: |:  .|:.....|:|:|||||||:.||.|.|.|.|:
Yeast   196 CFDTPSVKSTFTASIESP--LPVVFSGIRIEDTSKDTNIYRFEQKVPIPAYLIGIASGDLSSAPI 258

  Fly   284 GENSSVWAEEAIVDACAEEF-SETATMLKTATELCGPYVWKQYDLLVMPPSFPFGGMENPCLTFV 347
            |..|:|:.|...:..|..|| ::....::||.::...|.|..||:||...|:|:||||:|.:||.
Yeast   259 GPRSTVYTEPFRLKDCQWEFENDVEKFIQTAEKIIFEYEWGTYDILVNVDSYPYGGMESPNMTFA 323

  Fly   348 TPTLLAGDKSLADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQGAKELDFKML 412
            ||||:|.|:|..||:|||:||||:||||||.::.|||||||:||::|.:|:|.:.|.....|..|
Yeast   324 TPTLIAHDRSNIDVIAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSAL 388

  Fly   413 SNLTDLQECIRTQLNKTPE-LTKLVVDLS-NCGPDDAFSSVPYIKGSTFLRYLEDLFGGPTVFEP 475
            ...:|||..|.:.  |.|| .:.||.:|: |..||||||:|||.||...|.:||.:.||...|:|
Yeast   389 IGWSDLQNSIDSM--KDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFDP 451

  Fly   476 FLRDYLKKYAYKSIETKDFQSALYDYFIDTDKKDKLSAVDWDLWLKSEGMPPVIPNFDESLANVT 540
            |:|.|.||:|.||::|..|...||:::  .:||:.|.:|||:.||...|||| .|:|..:||:..
Yeast   452 FIRHYFKKFAKKSLDTFQFLDTLYEFY--PEKKEILDSVDWETWLYKPGMPP-RPHFITALADNV 513

  Fly   541 KELASLWSSKSVAELADSAEIKTT--------------ISIHQLIDFLGKL-------------- 577
            .:||..|     .|:|.  .:|||              .:.:||:.||..|
Yeast   514 YQLADKW-----VEMAQ--HLKTTEDFRSEFNAIDIKDFNSNQLVLFLETLTQNGHSNKKPKDFD 571

  Fly   578 -----IESKDIVDLNEGKINLLESTYNLKSSKNAEVRFRLNRLIIRARLIKRLDEILEFANSNFR 637
                 :.|:.::|:.:.         |:..|:||||.|::.:..|.|:|.:....:.::..:..|
Yeast   572 WAKFPVASRALLDIYQD---------NIVKSQNAEVVFKMFKFQIFAKLQEEYKHLADWLGTVGR 627

  Fly   638 MKFCRPIYRDLAGWPEAKPAAIRNFVNVKDQMMAVCSHTIEKDLGL 683
            |||.||.||.|..  ..:..|:..|...||....:|...:::||||
Yeast   628 MKFVRPGYRLLNS--VDRRLALATFDKFKDTYHPICKALVKQDLGL 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856	3/4 (75%)
		leuko_A4_hydro	79..681	CDD:274120	232/648 (36%)
LAP2	NP_014353.1	leuko_A4_hydro	57..669	CDD:274120	232/648 (36%)