Protein Alignment CG10602 and Anpep

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_112274.1
• Gene: Anpep / 81641
• RGDID: 2991
• Length: 965
• Species: Rattus norvegicus
• Alignment Length: 620
• Identity: 150/620 - (24%)
• Similarity: 227/620 - (36%)
• Gaps: 177/620 - (28%)

  Fly    80 PSSYS---QPDLITTEHSALNWKIDFAATKIQGSVLHRFKVLTAN--LDKILLDVRDINVTN--- 136
            |.||.   :|.|...|.....:|         ||...||   |.|  .:.|::..:.:|.||
  Rat    82 PDSYQVTLRPYLTPNEQGLYIFK---------GSSTVRF---TCNETTNVIIIHSKKLNYTNKGN 134

  Fly   137 --ATLLAGGSELPINFFISDAVDDIGQKLTLELPSGTAKGSLNVRIDYETSSSASG-----LQWL 194
              ..|.|.|.....|...::.|:.. :.|.:.|.....||.     .||..|...|     |...
  Rat   135 HRVALRALGDTPAPNIDTTELVERT-EYLVVHLQGSLVKGH-----QYEMDSEFQGELADDLAGF 193

  Fly   195 NPTQTL--GKEHPYMFSQCQAIHARSVIPCQDTPAVKFTYDATVEHPSELTALMSALIDKKEPGK 257
            ..::.:  |.:.....:|.||..||...||.|.||:|.:::.|:.||:.||||.:.|   .:..:
  Rat   194 YRSEYMEGGNKKVVATTQMQAADARKSFPCFDEPAMKASFNITLIHPNNLTALSNML---PKDSR 255

  Fly   258 TLFKQEVP------------IPAYLVAIAIGKL-----VSRPLGENSSVWAEEAIVDACAEEFSE 305
            ||  ||.|            :..||:|..:.:.     || |......:||..:.:|....::
  Rat   256 TL--QEDPSWNVTEFHPTPKMSTYLLAYIVSEFKYVEAVS-PNRVQIRIWARPSAIDEGHGDY-- 315

  Fly   306 TATMLKTATELCGP------------YVWKQYDLLVMPPSFPFGGMENPCLTFVTPTLLAGD--- 355
                   |.::.||            |..::.|.:.: |.|..|.|||..|.....:.|..|
  Rat   316 -------ALQVTGPILNFFAQHYNTAYPLEKSDQIAL-PDFNAGAMENWGLVTYRESALVFDPQS 372

  Fly   356 ------KSLADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQGAKELDFKMLSN 414
                  :.:..|:|||:||.|.|||||...:...||||||..:||  .:|........:.|.|..
  Rat   373 SSISNKERVVTVIAHELAHQWFGNLVTVDWWNDLWLNEGFASYVE--FLGADYAEPTWNLKDLIV 435

  Fly   415 LTDLQECI--------------RTQLNKTPELTKLVVDLSNCGPDDAFSSVPYIKGSTFLRYL-- 463
            |.|:...:              ..::|...::::|            |.|:.|.||::.||.|
  Rat   436 LNDVYRVMAVDALASSHPLSSPANEVNTPAQISEL------------FDSITYSKGASVLRMLSS 488

  Fly   464 ---EDLFGGPTVFEPFLRDYLKKYAYKSIETKDFQSALYDYF---IDTDKKDKLSA---VDWDLW 519
               |||      |:..|..||..:.|.:....|    |:::.   :|:....||.|   ...|.|
  Rat   489 FLTEDL------FKKGLSSYLHTFQYSNTIYLD----LWEHLQQAVDSQTAIKLPASVSTIMDRW 543

  Fly   520 LKSEGMPPVIPNFDESLANVTKELASLWSSKSVAELADSAEIKTTISIHQLIDFLGKLIESKD-- 582
            :...|.|.:..|  .|...:.:|                         |.|:|...|.....|
  Rat   544 ILQMGFPVITVN--TSTGEIYQE-------------------------HFLLDPTSKPTRPSDFN 581

  Fly   583 ------IVDLNEGKINLLESTYNLKSSKNAEVRFR 611
                  |..|..||    |..|.|::.||....|:
  Rat   582 YLWIVPIPYLKNGK----EDHYWLETEKNQSAEFQ 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856
		leuko_A4_hydro	79..681	CDD:274120	150/620 (24%)
Anpep	NP_112274.1	Cytosolic Ser/Thr-rich junction	33..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..68
		Metalloprotease	69..965		150/620 (24%)
		M1_APN-Q_like	84..545	CDD:341064	129/518 (25%)
		ERAP1_C	618..945	CDD:463368