Protein Alignment CG10602 and Erap1

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_109636.1
• Gene: Erap1 / 80898
• MGIID: 1933403
• Length: 930
• Species: Mus musculus
• Alignment Length: 677
• Identity: 150/677 - (22%)
• Similarity: 236/677 - (34%)
• Gaps: 168/677 - (24%)

  Fly   125 ILLDVRDINVTNATLLAGGSEL----PINFFISDAVDDIGQKLTLELPSGTAKGSLNVRIDYETS 185
            |::....:.::.|||..|..|:    |:......|.:.:.......|.:|:.   ..|.|||..:
Mouse    82 IIMHSHHLQISKATLRRGAGEMLSEEPLKVLEYPAHEQVALLAAQPLLAGSL---YTVIIDYAAN 143

  Fly   186 SSASGLQWLNPTQTL--GKEHPYMFSQCQAIHARSVIPCQDTPAVKFTYDATVEH-PSELTALMS 247
            .|.|...:...|...  |:......:|.:...||...||.|.||:|.::...::. |..|.....
Mouse   144 LSESFHGFYKSTYRTQEGEMRILAATQFEPTAARMAFPCFDEPALKASFSIKIKRDPRHLAISNM 208

  Fly   248 ALIDKKEPGKTL----FKQEVPIPAYLVAIAIG--KLVSR--PLGENSSVWAEEAIVDACAEEFS 304
            .|:......:.|    |...|.:..||||..|.  |.||:  ..|...||:|....::.......
Mouse   209 PLVKSVNVAEGLIEDHFDITVKMSTYLVAFIISDFKSVSKMTKSGVKVSVYAVPDKINQADYALD 273

  Fly   305 ETATMLKTATELCG-PYVWKQYDLLVMPPSFPFGGMENPCLTFVTPTLLAGDK---------SLA 359
            ...|:|:...:... ||...:.||..: |.|..|.|||..||....:.|..||         .:.
Mouse   274 AAVTLLEFYEDYFNIPYPLPKQDLAAI-PDFQSGAMENWGLTTYRESSLLYDKEKSSASSKLGIT 337

  Fly   360 DVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVF--------------VESKIVGRMQGAKELDFK 410
            .:|:||:||.|.|||||.:.:...||||||..|              ||....|:...|.|:|
Mouse   338 MIVSHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVTVTHPELKVEDYFFGKCFNAMEVD-- 400

  Fly   411 MLSNLTDLQECIRTQLNKTPELTKLVVDLSNCGPDDAFSSVPYIKGSTFLRYLEDLFGGPTVFEP 475
                ..:....:.|.:....::.::            |..|.|.||:..|..|.|.....| |:.
Mouse   401 ----ALNSSHPVSTPVENPAQIREM------------FDDVSYEKGACILNMLRDYLSADT-FKR 448

  Fly   476 FLRDYLKKYAYKSIETKDFQSALYDYFIDTD-----------KKDKLSAVDW-----------DL 518
            .:..||:||:||:.:.:|..:::. :...||           .:...|...|           :.
Mouse   449 GIVQYLQKYSYKNTKNEDLWNSMM-HICPTDGTQTMDGFCSRSQHSSSTSHWRQEVVDVKTMMNT 512

  Fly   519 WLKSEGMPPVIPNFDESLANV-------------TKELASLW-------SSKS------------ 551
            |...:|.|.:  ....|..||             ..|...||       :|||
Mouse   513 WTLQKGFPLI--TITVSGRNVHMKQEHYMKGSERFPETGYLWHVPLTFITSKSDSVQRFLLKTKT 575

  Fly   552 ----------------------VAELADSA---------EIKTTISIHQLIDFLGKLIESKDIVD 585
                                  :...||..         |..||||.:.....:....:...|..
Mouse   576 DVLILPEAVQWIKFNVGMNGYYIVHYADDGWASLSGLLKEAHTTISSNDRASLINNAFQLVSIEK 640

  Fly   586 LNEGKINLLESTYNLKSSKNAEVRFR-LNRLIIRARLIKRLDEI-LEFANSNFRMKFCRPIYRDL 648
            |:..|  .|:.|..||:.......|: ||.||...:|:::.|.| :|....:|.:|..:.:. |.
Mouse   641 LSIEK--ALDLTLYLKNETEIMPIFQALNELIPMYKLMEKRDMIEVETQFKDFLLKLLKDLI-DK 702

  Fly   649 AGWPEAKP-------------AAIRNF 662
            ..|.:...             |.:||:
Mouse   703 QTWTDEGSVSERMLRSQLLLLACVRNY 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856
		leuko_A4_hydro	79..681	CDD:274120	150/677 (22%)
Erap1	NP_109636.1	M1_APN-Q_like	50..515	CDD:341064	109/456 (24%)
		ERAP1_C	586..905	CDD:463368	30/147 (20%)