Protein Alignment CG10602 and Lvrn

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_083284.1
• Gene: Lvrn / 74574
• MGIID: 1921824
• Length: 991
• Species: Mus musculus
• Alignment Length: 722
• Identity: 157/722 - (21%)
• Similarity: 267/722 - (36%)
• Gaps: 186/722 - (25%)

  Fly    78 VDPSSYSQPDLITTEHSALNWKIDFAATKIQGSVLHRFKVLTANLDKILLDVRDINV-------- 134
            :.|...|.|:|..|....:..:...|::::   :||.|          ||:.:.:.|
Mouse   112 LQPDKLSPPNLTFTGRVNITVRCTVASSRL---LLHSF----------LLNYKQVEVWGPLAQDT 163

  Fly   135 TNATLLAGGSELPINFFISD---AVDDIGQKLTLELPSGTAKGSLNVRIDYETSSSASG--LQ-- 192
            .|||:  |..::...:|..|   .|.|:||.|        ..||     .||.|...||  ||
Mouse   164 RNATV--GRVQVEKVWFAPDMQFVVLDLGQSL--------EPGS-----RYELSFHFSGQVLQVG 213

  Fly   193 ----WLNPTQTLGKEHPYMFSQCQAIHARSVIPCQDTPAVKFTYDATV-EHPSELTALMSALIDK 252
                :||......:....:.:|.:...||.|.||.|.||:|.|::.|| .||.     .:||.:.
Mouse   214 LEGLFLNLYHDEDELRALVATQMEPTFARHVFPCFDEPALKATFNITVIHHPG-----YAALSNM 273

  Fly   253 KEPGK-------------TLFKQEVPIPAYLVAIAIGKL--VSR-PLGENSSVWAEEAIVDACAE 301
            .:.|:             |.|.....:|.||||:.:..|  :|| ..|:...|||.:   |..|.
Mouse   274 PQLGQSERIDVNGSRWTVTTFHTTPRMPTYLVALVVCDLDHISRTERGKEIRVWARK---DDIAS 335

  Fly   302 EFSETATMLKTATELCGP------------YVWKQYDLLVMPPSFPFGGMEN-PCLTFVTPTLLA 353
            .:      |..|..:.||            |...:.|::.: |.|..|.||| ..|.|...:||.
Mouse   336 GY------LDFAANITGPIFSFLEDLFNISYRLPKTDIVAL-PIFASGAMENWGLLIFDESSLLL 393

  Fly   354 GDKS--------LADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQGAKELD-- 408
            ..:.        :..::|||:.|.|.|||||...:.:.||||||..:.|.::.........::
Mouse   394 EPEDELTEKRAMILSIIAHEVGHQWFGNLVTMSWWNNIWLNEGFASYFELELTNYFYPKVPMNMI 458

  Fly   409 --FKMLSNLTDLQECIRTQ--------LNKTPELTKLVVDLSNCGPDDAFSSVPYIKGSTFLRYL 463
              |.:|..:......:.::        ..:|.|:.:|            |....|.||:. :.::
Mouse   459 FFFTVLHGILGEDHALESRAVSTAVENFTETSEINRL------------FDLYTYKKGAC-MAWM 510

  Fly   464 EDLFGGPTVFEPFLRDYLKKYAYKSIETKD----FQSALYDYFIDTDKKDKLSAVDWDLWLKSEG 524
            ...|..|.:|...|:.||:.::|.:.|..|    .|.|:.:..: |.....:..: .|.|....|
Mouse   511 LASFLSPHLFINALKSYLETFSYSNAEQDDLWRHIQMAIGEQNV-THLPATVKGI-MDSWTHRGG 573

  Fly   525 MPPVIPNFDESLA------------------NVTKELASLWSSKSVAE----------------L 555
            .|.:..|....:.                  |.|..:...|....:.:                |
Mouse   574 FPIITVNVSTGVVKQEPFYLDKVENQTLLSHNSTWIVPIFWMKNGIPQPLVWLDKSNMMFPGMKL 638

  Fly   556 ADSAE----IKTTISIHQLIDF--LG--KLIES-----KDIVDLNEGKINLLESTYNLKSSKNAE 607
            :||..    :...::.:..:::  ||  ||.|.     |.|..:|  ::.|:...:.|..:...|
Mouse   639 SDSDSDWVILNFNVTGYYRVNYDELGWKKLSEQLEKDPKAIPVIN--RLQLVSDAFALTKNNYIE 701

  Fly   608 VRFRLNRLIIRARLIKRLDEILEFANSNFRMKFCRPIY--RDLAGWPEAKPAAIRNFVNVKDQMM 670
            :...|:    ..:.|...||||.:......:.....||  .:.|.:|..|...::.|.::.:...
Mouse   702 IETALD----LTKYIAEEDEILVWFEVLLNLINREVIYDVNNYALYPLLKKYLLKRFNSIWNTYS 762

  Fly   671 AVCSHTI 677
            |:....:
Mouse   763 AIIRENV 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856
		leuko_A4_hydro	79..681	CDD:274120	157/721 (22%)
Lvrn	NP_083284.1	M1_APN-Q_like	102..570	CDD:341064	124/515 (24%)
		ERAP1_C	645..964	CDD:463368	24/131 (18%)