Protein Alignment CG10602 and Aopep

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001276853.1
• Gene: Aopep / 72061
• MGIID: 1919311
• Length: 823
• Species: Mus musculus
• Alignment Length: 687
• Identity: 156/687 - (22%)
• Similarity: 272/687 - (39%)
• Gaps: 153/687 - (22%)

  Fly    86 PDLITTEHSALNWKIDFAATKIQGSVLHRFKVLTANLDKILLDVRDINVTNATLLAGGSELPINF 150
            |.|:.|..            |::..::.....|.|:..:..||.    .|..:...|..||.|:
Mouse   174 PKLLATPE------------KLRCEIVRDLVALPADAWREQLDC----YTRCSQAPGCGELLID- 221

  Fly   151 FISD----AVDDIGQKLTLELPSGTAKGSLNVRIDYETSSSASGLQWLNPTQTLGKEHPYMFSQC 211
              ||    .:...|.....:.|..       :||.|:|......:.|  .|...|:  |.:::..
Mouse   222 --SDNWSLRIRKTGTSTPADFPRA-------IRIWYKTKPEGQSVAW--TTDQNGR--PCVYTMG 273

  Fly   212 QAIHARSVIPCQDTPAVKFTYDATVEHPSELTALMSALIDKKEPGKTLFKQ---------EVPIP 267
            ..|:.|::.|||:.|....|:.|||...:....|||.   :.....|..::         .:|:|
Mouse   274 SPINNRALFPCQEPPVAMSTWQATVRAAASFVVLMSG---ENSAKPTPLREGYMSWHYYVTMPMP 335

  Fly   268 AYLVAIAIGKLV----------------SRPLG---------------------ENSSVWAEEAI 295
            |...|||:|...                |.||.                     :::|..:::.|
Mouse   336 ASTFAIAVGCWTEMKPKASPPDDLMTEHSLPLSPSEADLRYDNTCNHMEYPCRFQSASAASQDII 400

  Fly   296 -----VDACAEEFSETATM------LKTATELCGPYVWKQYDLLVMPPSFPFGGMENPCLTFVTP 349
                 ...|.|...:.|.:      |..|..:.|.:.:.:.|:|::|.:||..||.:|.:.|::.
Mouse   401 PYRVFAPVCLEGACQEALLWLIPSCLSAAHSVLGTHPFSRLDILIVPTNFPSLGMASPHIIFLSQ 465

  Fly   350 TLLAGDKSLADV-VAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQGAKELDFKMLS 413
            :.|.|...|... :.|||||||.|..:..:::...||:|||...:|......   |::|......
Mouse   466 STLTGTSHLCGTRLCHEIAHSWFGLAIGARDWTEEWLSEGFATHLEDIFWAE---AQQLPPHEAL 527

  Fly   414 NLTDLQECIR-----TQLNKTPELTKLV---------VDLSNC-------GPDDAFSSVPYIKGS 457
            ...:|:.|:|     .:|..:||..:::         |..|..       .|:..|..|.|:||.
Mouse   528 EQQELRACLRWHRLQDELRNSPEGMQVLRPNKEETGHVSASGASVVKHGLNPEKGFMQVHYLKGY 592

  Fly   458 TFLRYLEDLFGGPTVFEPFLRDYLKKYAYKSIETKDFQSALYDYFIDTDKKDKLSA--VDWDLWL 520
            ..||:|.... |..::.||||.::..:..:.|.::||...|.:. |..:|:..||.  :..| ||
Mouse   593 FLLRFLTRTL-GEKIYFPFLRKFVHLFHGQLILSQDFLQMLLEN-IPENKRLGLSVENIVRD-WL 654

  Fly   521 KSEGMPPVIPN----FDESLANVTKELAS---LW---------SSKSVAELADSAEIKTTISIHQ 569
            :..|:|..:..    .|.|.:.:.:::.|   .|         ..:...|:|..     .:|..|
Mouse   655 ECSGIPKALQEERKAEDCSPSRLARQVGSEVAKWIRVNRRPRKRKRGKREVAFE-----KLSPDQ 714

  Fly   570 LIDFLGKLIESKDIVDLNEGKINLLESTYNLKSSKNAEVRFRLNRLIIRARLIKRLDEILEFANS 634
            ::..|..|:|.|   .|:...::.|:.||:| ..::||||.|...|:|:.:..|..:::..|...
Mouse   715 IVLLLEWLLEQK---TLSPQTLHCLQQTYHL-PEQDAEVRHRWCELVIKHKYTKAYNQVERFLLE 775

  Fly   635 NFRMKFCRPIYRDLAGWPEAK--PAAIRNFVNVKDQM 669
            :..|...  :|.:|....:|:  ..|.|.|..||:.|
Mouse   776 DQAMGIY--LYGELMVSEDARLQQLAHRCFELVKEHM 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856
		leuko_A4_hydro	79..681	CDD:274120	156/687 (23%)
Aopep	NP_001276853.1	GluZincin	<244..641	CDD:472708	95/408 (23%)
		Nucleolar localization signal. /evidence=ECO:0000269|PubMed:17803194	693..703		0/9 (0%)
		Leuk-A4-hydro_C	710..822	CDD:462686	30/107 (28%)