Protein Alignment CG10602 and RNPEP

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_064601.3
• Gene: RNPEP / 6051
• HGNCID: 10078
• Length: 650
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 215/557 - (38%)
• Similarity: 315/557 - (56%)
• Gaps: 28/557 - (5%)

  Fly   132 INVTNATLL--AGGSE----LPINFFISDAVDDIGQKLTLELPSG-TAKGSLNVRIDYETSSSAS 189
            :.||.|.|.  ..|||    .|::|: :......||.|.:..|.. .|...|.|.:.|.. ....
Human    86 LEVTAAALRRERPGSEEPPAEPVSFY-TQPFSHYGQALCVSFPQPCRAAERLQVLLTYRV-GEGP 148

  Fly   190 GLQWLNPTQTLGKEHPYMFSQCQAIHARSVIPCQDTPAVKFTYDATVEHPSELTALMSALI-DKK 253
            |:.||.|.||.||:.|::::|.||:..|:..||.||||||:.|.|.:|.|...||:|||.. :|:
Human   149 GVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKR 213

  Fly   254 EPGKTLFKQEVPIPAYLVAIAIGKLVSRPLGENSSVWAEEAIVDACAEEFSET-ATMLKTATELC 317
            .|.|..|:...|||:||:|:|||.|||..:|..|.||||..::||..||::.. ...|.|..:|.
Human   214 GPNKFFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLF 278

  Fly   318 GPYVWKQYDLLVMPPSFPFGGMENPCLTFVTPTLLAGDKSLADVVAHEIAHSWTGNLVTNKNFEH 382
            |||||.:||||.||||||||||||||||||||.|||||:|||||:.|||:|||.||||||.|:..
Human   279 GPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGE 343

  Fly   383 FWLNEGFTVFVESKIVGRMQGAKELDFKMLSNLTDLQECIRTQLNKTPE---LTKLVVDLS-NCG 443
            ||||||||::.:.:|...:.||.   :..|...|. :..:|..::.|.|   |.||.|.:. ...
Human   344 FWLNEGFTMYAQRRISTILFGAA---YTCLEAATG-RALLRQHMDITGEENPLNKLRVKIEPGVD 404

  Fly   444 PDDAFSSVPYIKGSTFLRYLEDLFGGPTVFEPFLRDYLKKYAYKSIETKDFQSALYDYFIDTDKK 508
            |||.::..||.||..|:.||..|.|....|:.||:.|:.::.::||...||.....:||.:..||
Human   405 PDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKK 469

  Fly   509 --DKLSAVDWDLWLKSEGMPPVIPNFD--ESLANVTKELASLWSSKSVAELADSAEIKTTISIHQ 569
              |.:...::|.||.:.|.||.:|:..  :||....:|||.||:::.:...|..|...:....:|
Human   470 RVDIIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQ 534

  Fly   570 LIDFLGKLIESKDIVDLNEGKINLLESTY-NLKSSKNAEVRFRLNRLIIRARLIKRLDEILEFAN 633
            |:.||.|:::..   .|..|.:..|..|| ::.:::|||:|.|..:::::....:...::.||.:
Human   535 LVYFLDKILQKS---PLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLH 596

  Fly   634 SNFRMKFCRPIYRDLAGWPE-AKPAAIRNFVNVKDQM 669
            :..:.|:..|:|..:.|..| |:..|...|.:...|:
Human   597 NQGKQKYTLPLYHAMMGGSEVAQTLAKETFASTASQL 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856
		leuko_A4_hydro	79..681	CDD:274120	215/557 (39%)
RNPEP	NP_064601.3	M1_LTA4H	24..484	CDD:341062	175/403 (43%)
		Leuk-A4-hydro_C	530..644	CDD:462686	26/107 (24%)