Protein Alignment CG10602 and Lta4h

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001025202.1
• Gene: Lta4h / 299732
• RGDID: 1311333
• Length: 611
• Species: Rattus norvegicus
• Alignment Length: 622
• Identity: 274/622 - (44%)
• Similarity: 384/622 - (61%)
• Gaps: 34/622 - (5%)

  Fly    77 VVDPSSYSQP-DLITTEHSALNWKIDFAATKIQGSVLHRFKVLTANLDKILLDVRDINVTNATLL 140
            |.|..|.:.| .:..|:|..|...:|||...:.|:.....:....||..:.||.:|:.:....:
  Rat     4 VADTCSLASPASVCRTQHLHLRCSVDFARRALTGTAALTVQSQEDNLRSLTLDTKDLTIEKVVI- 67

  Fly   141 AGGSELPINFFISDAVDDIGQKLTLELPSGTAKG-SLNVRIDYETSSSASGLQWLNPTQTLGKEH 204
             .|.|  :.:.:.::....|..:.:.||...:|. .:.:.|.:|||..:|.||||.|.||.||:|
  Rat    68 -NGQE--VKYTLGESQGYKGSPMEISLPIALSKNQEVVIEISFETSPKSSALQWLTPEQTSGKQH 129

  Fly   205 PYMFSQCQAIHARSVIPCQDTPAVKFTYDATVEHPSELTALMSAL-----IDKKEPGKTL--FKQ 262
            ||:||||||||.|:::||||||:||.||.|.|..|.||.|||||:     .|.::|.:.:  |.|
  Rat   130 PYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGEAPDPEDPSRKIYRFNQ 194

  Fly   263 EVPIPAYLVAIAIGKLVSRPLGENSSVWAEEAIVDACAEEFSETATMLKTATELCGPYVWKQYDL 327
            .||||.||:|:.:|.|.||.:|..:.||:|:..|:..|.|||||.:|||.|.:|.|||||.||||
  Rat   195 RVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDL 259

  Fly   328 LVMPPSFPFGGMENPCLTFVTPTLLAGDKSLADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVF 392
            ||:|||||:||||||||||||||||||||||::|:||||:|||||||||||.::|||||||.||:
  Rat   260 LVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVY 324

  Fly   393 VESKIVGRMQGAKELDFKMLSNLTDLQECIRTQLNKTPELTKLVVDLSNCGPDDAFSSVPYIKGS 457
            :|..|.||:.|.|...|..|....:||..|:| ..::...|||||||.:..||.|:||:||.||.
  Rat   325 LERHICGRLFGEKFRHFHALGGWGELQNTIKT-FGESHPFTKLVVDLKDVDPDVAYSSIPYEKGF 388

  Fly   458 TFLRYLEDLFGGPTVFEPFLRDYLKKYAYKSIETKDFQSALYDYFIDTDKKDKLSAVDWDLWLKS 522
            ..|.|||.|.|||.||..||:.|::|::|:|:.|.|::|.||.:|  .||.|.|:.|||:.||.:
  Rat   389 ALLFYLEQLLGGPEVFLGFLKAYVEKFSYQSVTTDDWKSFLYAHF--KDKVDLLNQVDWNAWLYA 451

  Fly   523 EGMPPVIPNFDESLANVTKELASLW--------SSKSVAELADSAEIKTTISIHQLIDFLGKLIE 579
            .|:|||.||:|.:|.|....|:..|        :|.|:.:|.|       :|.|||.:||.::::
  Rat   452 PGLPPVKPNYDVTLTNACIALSQRWVTAKEEDLNSFSIEDLKD-------LSSHQLNEFLAQVLQ 509

  Fly   580 SKDIVDLNEGKINLLESTYNLKSSKNAEVRFRLNRLIIRARLIKRLDEILEFANSNFRMKFCRPI 644
            .   ..|..|.|..::..||..:..|:|:|||..||.|:::..:.:...|:.|....||||.||:
  Rat   510 K---APLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEEAIPLALKMATEQGRMKFTRPL 571

  Fly   645 YRDLAGWPEAKPAAIRNFVNVKDQMMAVCSHTIEKDL 681
            ::|||.:.::...|:|.:...|..|..|.:..:.|||
  Rat   572 FKDLAAFDKSHDQAVRTYQEHKACMHPVTAMLVGKDL 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856
		leuko_A4_hydro	79..681	CDD:274120	271/618 (44%)
Lta4h	NP_001025202.1	leuko_A4_hydro	6..608	CDD:274120	271/618 (44%)