Protein Alignment CG10602 and Lnpep

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_766415.1
• Gene: Lnpep / 240028
• MGIID: 2387123
• Length: 1025
• Species: Mus musculus
• Alignment Length: 669
• Identity: 156/669 - (23%)
• Similarity: 262/669 - (39%)
• Gaps: 155/669 - (23%)

  Fly    55 LCTSHKLLPIYQVQKRNMGRLGVVDPSSYSQPDLITTEHSALNWKIDFAATKIQGSVLHRFKVLT 119
            :.|:.|:.|..|::...     .:.|..|.           |:...:..:...:|||       |
Mouse   154 VATNGKVFPWAQIRLPT-----AIIPLCYE-----------LSLHPNLTSMTFRGSV-------T 195

  Fly   120 ANLDKILLDVRDI-------NVTNATLLAGGS---------ELPINFFISDAVDDIGQKLTLELP 168
            .:| :.|.|.|||       |::..|.::..|         |.|.:           :::.:..|
Mouse   196 ISL-QALQDTRDIILHSTGHNISRVTFMSAVSSQEKQVEILEYPYH-----------EQIAVVAP 248

  Fly   169 SGTAKG-SLNVRIDYET--SSSASGLQWLNPTQTLGKEHPYMFSQCQAIHARSVIPCQDTPAVKF 230
            .....| :..::|:|..  |:|..|...:..|....::..:..:|.:.:.|||..||.|.||.|.
Mouse   249 EPLLTGHNYTLKIEYSANISNSYYGFYGITYTDKSNEKKYFAATQFEPLAARSAFPCFDEPAFKA 313

  Fly   231 TYDATVEHPSELTALMSALIDKK-----EPG--KTLFKQEVPIPAYLVAIAIGKLVSRPLGENSS 288
            |:...:......|||.:  :.||     |.|  :..|.:.|.:..||||..:|::.:.....|.:
Mouse   314 TFIIKITRNEHHTALSN--MPKKSSVPAEEGLIQDEFSESVKMSTYLVAFIVGEMRNLSQDVNGT 376

  Fly   289 VWAEEAIVDACAEEFSETATMLKTATELCGPYVWKQYDL----LVMPPSFPFGGMEN-PCLTFVT 348
            :.:..|:.:...:......|.:| ..|....|...||.|    ||..|.|..|.||| ..|||..
Mouse   377 LVSVYAVPEKIGQVHHALDTTIK-LLEFYQTYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFRE 440

  Fly   349 PTLL--------AGDKSLADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQGAK 405
            .|||        |..|.:..::|||:||.|.|||||.:.:...||||||..|:|...|.::
Mouse   441 ETLLYDNATSSVADRKLVTKIIAHELAHQWFGNLVTMQWWNDLWLNEGFATFMEYFSVEKI---- 501

  Fly   406 ELDFKMLSNLTDLQEC-----IRTQLNKTPELTKLVVDLSNCGPDDAFSSVPYIKGSTFLRYL-- 463
               ||.|::..|..:.     .:..||.:..::..|......  ::.|.|:.|.||::.|..|
Mouse   502 ---FKELNSYEDFLDARFKTMRKDSLNSSHPISSSVQSSEQI--EEMFDSLSYFKGASLLLMLKS 561

  Fly   464 ---EDLFGGPTVFEPFLRDYLKKYAYKSIETKDFQSALYDYFID-TDKKDKLSAVDWDLWLKSEG 524
               ||:|....:.      ||..::|.:|::.|    |:|.|.: |||...:..: ...|...:|
Mouse   562 YLSEDVFRHAVIL------YLHNHSYAAIQSDD----LWDSFNEVTDKTLDVKKM-MKTWTLQKG 615

  Fly   525 MPPVI--------------------PNFDESLANVTKELASLWSSKSVAELADSAEIKTTISIHQ 569
            .|.|.                    |....|      :.:.||.. .::.:.|........|: .
Mouse   616 FPLVTVQRKGTELLLQQERFFLRMQPESQPS------DTSHLWHI-PISYVTDGRNYSEYRSV-S 672

  Fly   570 LIDFLGKLIESKDIVDLNEG----KINLLESTYNLKSSKNAEVRFRLNRL-----II----RARL 621
            |:|      :..|:::|.|.    |:|...:.|.:....:.:....:|:|     ::    ||.|
Mouse   673 LLD------KKSDVINLTEQVQWVKVNSNMTGYYIVHYAHDDWTALINQLKRNPYVLSDKDRANL 731

  Fly   622 IKRLDEILEFANSNFRMKF 640
            |..:.|:........||.|
Mouse   732 INNIFELAGLGKVPLRMAF 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856
		leuko_A4_hydro	79..681	CDD:274120	152/645 (24%)
Lnpep	NP_766415.1	Dileucine internalization motif. /evidence=ECO:0000255	53..54
		Dileucine internalization motif. /evidence=ECO:0000255	76..77
		Tankyrase binding. /evidence=ECO:0000250	96..101
		M1_APN-Q_like	177..612	CDD:341064	124/487 (25%)
		ERAP1_C	689..1009	CDD:463368	13/62 (21%)