Protein Alignment CG10602 and LVRN

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_776161.3
• Gene: LVRN / 206338
• HGNCID: 26904
• Length: 990
• Species: Homo sapiens
• Alignment Length: 692
• Identity: 167/692 - (24%)
• Similarity: 253/692 - (36%)
• Gaps: 225/692 - (32%)

  Fly   156 VDDI-----GQKLTLELPSGTAKGSLNVRIDYETSSSASGL--------QWLNPTQTLGKEHPYM 207
            |||:     .:.:.|||......||     .||...|.|||        .:||.....|:....:
Human   176 VDDVWFALDTEYMVLELSEPLKPGS-----SYELQLSFSGLVKEDLREGLFLNVYTDQGERRALL 235

  Fly   208 FSQCQAIHARSVIPCQDTPAVKFTYDAT-VEHPSELTALMSALIDKKEPGK-------------T 258
            .||.:...||.|.||.|.||:|.|::.| :.|||.:     ||.:..:.|:             |
Human   236 ASQLEPTFARYVFPCFDEPALKATFNITMIHHPSYV-----ALSNMPKLGQSEKEDVNGSKWTVT 295

  Fly   259 LFKQEVPIPAYLVAIAIGKL--VSR-PLGENSSVWA-EEAIVDACAEEFSETATMLKTATELCGP 319
            .|.....:|.||||..|...  |:| ..|:...:|| ::||.:..|:          .|..:.||
Human   296 TFSTTPHMPTYLVAFVICDYDHVNRTERGKEIRIWARKDAIANGSAD----------FALNITGP 350

  Fly   320 ------------YVWKQYDLLVMPPSFPFGGMEN-PCLTFVTPTLLAGDKS--------LADVVA 363
                        |...:.|::.: |||....||| ..:.|....||...|.        ::.||:
Human   351 IFSFLEDLFNISYSLPKTDIIAL-PSFDNHAMENWGLMIFDESGLLLEPKDQLTEKKTLISYVVS 414

  Fly   364 HEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQ---GAKELDF-KMLSNLTDLQE---- 420
            |||.|.|.|||||...:.:.||||||..:.|.:::....   ...|:.| .:|.|:  |:|
Human   415 HEIGHQWFGNLVTMNWWNNIWLNEGFASYFEFEVINYFNPKLPRNEIFFSNILHNI--LREDHAL 477

  Fly   421 -----CIRTQLNKTPELTKLVVDLSNCGPDDAFSSVPYIKGSTFLRYLEDLFGGPTVFEPFLRDY 480
                 .::.:..||.|:.:|            |....|.||::..|.| ..|....:|...|:.|
Human   478 VTRAVAMKVENFKTSEIQEL------------FDIFTYSKGASMARML-SCFLNEHLFVSALKSY 529

  Fly   481 LKKYAYKSIETKD----FQSALYD---YFIDTDKKDKLSAVDWDLWLKSEGMPPVI--------- 529
            ||.::|.:.|..|    ||.|:.|   ..:....|:.:     |.|....|.|.:.
Human   530 LKTFSYSNAEQDDLWRHFQMAIDDQSTVILPATIKNIM-----DSWTHQSGFPVITLNVSTGVMK 589

  Fly   530 --PNFDESLANVTKELAS-------LW--------------SSKSVAEL--ADS----------- 558
              |.:.|::.|.|...::       ||              |||...|:  :||
Human   590 QEPFYLENIKNRTLLTSNDTWIVPILWIKNGTTQPLVWLDQSSKVFPEMQVSDSDHDWVILNLNM 654

  Fly   559 ---------------------AEIKTTISIH--QLID---FLGK---------------LIESKD 582
                                 .:.|....||  ||||   .|.|               |.|..:
Human   655 TGYYRVNYDKLGWKKLNQQLEKDPKAIPVIHRLQLIDDAFSLSKNNYIEIETALELTKYLAEEDE 719

  Fly   583 IVDLNEGKINL----LESTYNLKSSKNAEVRFRLNRL---------IIRARLIKRLDEILEFANS 634
            |:..:...:||    |.|..|:....:...|:.|.||         |||..::...|:.|...:.
Human   720 IIVWHTVLVNLVTRDLVSEVNIYDIYSLLKRYLLKRLNLIWNIYSTIIRENVLALQDDYLALISL 784

  Fly   635 N--------FRMKFCRPIYRDL-AGW---PEAK-PAAIRNFV 663
            .        ..::.|..:.::| |.|   ||.: |..|::.|
Human   785 EKLFVTACWLGLEDCLQLSKELFAKWVDHPENEIPYPIKDVV 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856
		leuko_A4_hydro	79..681	CDD:274120	167/692 (24%)
LVRN	NP_776161.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..91
		M1_APN-Q_like	105..572	CDD:341064	118/436 (27%)
		ERAP1_C	647..970	CDD:463368	35/180 (19%)