Protein Alignment CG10602 and ENPEP

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001968.3
• Gene: ENPEP / 2028
• HGNCID: 3355
• Length: 957
• Species: Homo sapiens
• Alignment Length: 526
• Identity: 138/526 - (26%)
• Similarity: 211/526 - (40%)
• Gaps: 122/526 - (23%)

  Fly    82 SYSQPDLITTEHSALNWKIDFAATKIQGSVLHRFKVLTANLDKILLDVRDINVTNATLLAGGSEL 146
            ::..||.:...|..|:.|.........|:|..... |:|....:.|.:|:..:|         .|
Human    90 NFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISIN-LSAPTRYLWLHLRETRIT---------RL 144

  Fly   147 PINFFISDAVDDIGQKLTLELPSGTAKGSLNVRIDYE---------------TSSSASGLQ---- 192
            |                .|:.|||   ..:.||..:|               |.||..||.
Human   145 P----------------ELKRPSG---DQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTM 190

  Fly   193 ----WLNPT-----QTLGKEHPYMFSQCQAIH----ARSVIPCQDTPAVKFTYDATVEHPSELTA 244
                |||.:     :|...|:..:.|.....|    ||...||.|.|..|.||..::.||.|..|
Human   191 EFAGWLNGSLVGFYRTTYTENGQVKSIVATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGA 255

  Fly   245 LMSALIDKKEP-----GKTLFKQEVPIPAYLVAIAIGKLVSRPLGENSS------VWAEEAIVDA 298
            |.:..:.|:|.     .:|.|::.||:..|||..|:.:..|.....||.      |..|:.....
Human   256 LSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAE 320

  Fly   299 CAEEFSETATMLKTATELCGPYVWKQYDL----LVMPPSFPFGGMEN-PCLTFVTPTLL------ 352
            .|      |.:.|:..:....|....|.|    .:..|.|..|.||| ..:|:....||
Human   321 YA------ANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKES 379

  Fly   353 --AGDKSLADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQGAKELDFKMLSNL 415
              :..:.:|.|||||:.|.|.||:||...:|..||||||..|.|...|..    .|.|::|...:
Human   380 ASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNH----AETDWQMRDQM 440

  Fly   416 TDLQECIRTQ-----LNKTPELTKLVVDLSNCGPDD---AFSSVPYIKGSTFLRYLEDLFGGPTV 472
            . |::.:..|     ::..|    ::|.::.  ||:   .|..:.|.|||:.||.|||.. .|..
Human   441 L-LEDVLPVQEDDSLMSSHP----IIVTVTT--PDEITSVFDGISYSKGSSILRMLEDWI-KPEN 497

  Fly   473 FEPFLRDYLKKYAYKSIETKDFQSALYDYFIDTDKKDKLSAVD-WDLWLKSEGMPPVIPNFDESL 536
            |:...:.||:||.:|:.:|.||.:||       ::..:|...: .|.|.:..|.|.:..|   .:
Human   498 FQKGCQMYLEKYQFKNAKTSDFWAAL-------EEASRLPVKEVMDTWTRQMGYPVLNVN---GV 552

  Fly   537 ANVTKE 542
            .|:|::
Human   553 KNITQK 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856
		leuko_A4_hydro	79..681	CDD:274120	138/526 (26%)
ENPEP	NP_001968.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..83
		M1_APN-Q_like	100..540	CDD:341064	131/493 (27%)
		ERAP1_C	616..934	CDD:463368