Protein Alignment CG10602 and T16G12.1

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_499230.2
• Gene: T16G12.1 / 176416
• WormBaseID: WBGene00011803
• Length: 1890
• Species: Caenorhabditis elegans
• Alignment Length: 712
• Identity: 167/712 - (23%)
• Similarity: 269/712 - (37%)
• Gaps: 147/712 - (20%)

  Fly    47 HPMISTRGLCTSHKLLPIYQVQKRNMGRLGVVDPSSYSQPDLITTEHSALNWKIDFAATK---IQ 108
            ||....:....:.|...:|..:.|....|..:|.|.:.||...:.       .:.:|..|   ..
 Worm    57 HPDNFRQDKLAARKRQSLYVTKTRLPPNLYAIDYSLWFQPYFPSP-------GVQYAPEKNFTFD 114

  Fly   109 GSVLHRFKVLTANLDKILLDVRDINVTNATLL-AGGSELPINFFISDAVDDIGQKLTL-ELPSGT 171
            |....:.:.|.|: |:.:|:..:..:.:..:: ..|:.:|||   |.:.||..|:|:| ...:|.
 Worm   115 GRASIQVEALVAS-DRFILNAYNFKIQSYKVVDIDGTVVPIN---SISQDDTTQQLSLITNANGV 175

  Fly   172 AKGSL-NVRIDYE---TSSSASGLQWLNPTQTLGKEHPYMFSQCQAIHARSVIPCQDTPAVKFTY 232
            ..|.: |:...|.   ...:..|:.:.:.....|..|..:.:..:...||.|.|..|.|:.|..:
 Worm   176 VAGQIYNIEFVYTGIINPYTDGGVYYTSYNDPQGNTHYMIATHMEPFSARKVFPSLDEPSYKAKF 240

  Fly   233 DATVEHPSELTALMSALIDKKEPGK-------TLFKQEVPIPAYLVAIAIGKLV-SRPLGENSSV 289
            ..||::|:...||.:.:  :.||.|       ..|.|...:.:||:|.|:|..| |:.:.:::::
 Worm   241 TITVQYPASQVALSNMM--ETEPTKIDNIWSTITFPQTPKMSSYLIAFAVGPYVNSQYVNKHNTL 303

  Fly   290 -----W-AEEAIVDACAEEFSETATMLKTATELCGPYVWKQYDLLVMPPSFPFGGMENPCLTF-- 346
                 | ..|..:...|:...|....|...|.:..|.  .:.|.|.| |.|..|.|||..|..
 Worm   304 TRAWGWPGTEQYLQFAAQNAGECLYQLGEYTGIKFPL--SKADQLGM-PEFLAGAMENWGLIIYK 365

  Fly   347 -----VTPTLLA--GDKSLADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFT----VFVESKIVGR 400
                 ..||.:.  ..::.|.|:.||:||.|.|:|||...::..:|||||.    .|::..:.
 Worm   366 YQYIAYNPTTMTTRNMEAAAKVMCHELAHQWFGDLVTTAWWDDLFLNEGFADYFMTFIQKSVY-- 428

  Fly   401 MQGAKELDFKMLSNLTDLQECIRTQLNKTPELTKLVVDLSNCGPD-DAFSSVPYIKGSTFLRYLE 464
            .|.|..||  .|..|.:||..:...:..  :...||.      || .||..:.|.||::.||.|.
 Worm   429 PQQATYLD--TLQVLDELQVGLTADVRY--DAHPLVY------PDGPAFDDITYNKGASMLRMLS 483

  Fly   465 DLFGGPTVFEPFLRDYLKKYAYKSIETKDFQSALYD-----------------------YFIDT- 505
            |:.|. .||:..:|.||:|..|.:....|..|.|.|                       |...|
 Worm   484 DVLGA-DVFKQGIRAYLQKMQYSNANDFDLFSTLTDTAKSNNILDWCGLPLNVTDFMQPYIHQTN 547

  Fly   506 -----------------------DKKDKLSAVDWDL-------------------WL-KSEGMPP 527
                                   |..| |:|..|:.                   || :.:|...
 Worm   548 HPLIRYNNNQKIGGSTFSQEPFLDISD-LTATPWNYTWSIPLTSANLRHADPYKQWLPRQQGCAN 611

  Fly   528 VIPNFDESLANVTKELASLWSSKSVAELADSAEIKTTISIHQLIDFLGKLIESKDIVDLNEGKIN 592
            :..|..|.......:.|..|...|:........|...|...:::    |||:..||.|  ..|:.
 Worm   612 MNENIQEERIKEPNKRAVQWELTSITSATYGRIIYDDIGFDRIL----KLIKQDDIND--NLKLT 670

  Fly   593 LLESTYN-LKSSKNAEVRFRLNRLIIRARLIKRLDEILE------FANSNFRMKFCRPIYRD 647
            ||...|| :...|.|...|..||.:..|::|........      ||.:...::....:|||
 Worm   671 LLADEYNYMLREKKANRPFGYNRFLDLAKVIFNTQSFTNYPSYGVFAQAQPVLEQIAQLYRD 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856	2/2 (100%)
		leuko_A4_hydro	79..681	CDD:274120	161/680 (24%)
T16G12.1	NP_499230.2	M1_APN-Q_like	90..544	CDD:341064	121/482 (25%)
		ERAP1_C	639..931	CDD:463368	25/100 (25%)
		M1_APN-Q_like	1005..1471	CDD:341064
		ERAP1_C	1542..1839	CDD:463368