Protein Alignment CG10602 and Lnpep

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001106874.1
• Gene: Lnpep / 171105
• RGDID: 621752
• Length: 1025
• Species: Rattus norvegicus
• Alignment Length: 669
• Identity: 159/669 - (23%)
• Similarity: 266/669 - (39%)
• Gaps: 155/669 - (23%)

  Fly    55 LCTSHKLLPIYQVQKRNMGRLGVVDPSSYSQPDLITTEHSALNWKIDFAATKIQGSVLHRFKVLT 119
            :.|:.|:.|..|:      ||          |..|..:...|:...:..:...:|||       |
  Rat   154 IATNGKVFPWAQI------RL----------PTAIIPQRYELSLHPNLTSMTFRGSV-------T 195

  Fly   120 ANLDKILLDVRDI-------NVTNATLLAGGS---------ELPINFFISDAVDDIGQKLTLELP 168
            .:| :.|.|.|||       |:::.|.::..|         |.|.:           :::.:..|
  Rat   196 ISL-QALQDTRDIILHSTGHNISSVTFMSAVSSQEKQVEILEYPYH-----------EQIAVVAP 248

  Fly   169 SGTAKG-SLNVRIDYET--SSSASGLQWLNPTQTLGKEHPYMFSQCQAIHARSVIPCQDTPAVKF 230
            .....| :..::|:|..  |:|..|...:..|....::..:..:|.:.:.|||..||.|.||.|.
  Rat   249 ESLLTGHNYTLKIEYSANISNSYYGFYGITYTDKSNEKKNFAATQFEPLAARSAFPCFDEPAFKA 313

  Fly   231 TYDATVEHPSELTALMSALIDKK-----EPG--KTLFKQEVPIPAYLVAIAIGKL--VSRPL-GE 285
            |:...:......|||.:  :.||     |.|  :..|.:.|.:..||||..:|::  :|:.: |.
  Rat   314 TFIIKITRDEHHTALSN--MPKKSSVPTEEGLIQDEFSESVKMSTYLVAFIVGEMRNLSQDVNGT 376

  Fly   286 NSSVWAEEAIVDACAEEFSETATMLKTATELCGPYVWKQYDL----LVMPPSFPFGGMEN-PCLT 345
            ..||:|....:|........|..:|    |....|...||.|    ||..|.|..|.||| ..||
  Rat   377 LVSVYAVPEKIDQVYHALDTTVKLL----EFYQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLT 437

  Fly   346 FVTPTLL--------AGDKSLADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQ 402
            |...|||        |..|.:..::|||:||.|.|||||.:.:...||||||..|:|...|.::
  Rat   438 FREETLLYDNATSSVADRKLVTKIIAHELAHQWFGNLVTMQWWNDLWLNEGFATFMEYFSVEKI- 501

  Fly   403 GAKELDFKMLSNLTDLQEC-----IRTQLNKTPELTKLVVDLSNCGPDDAFSSVPYIKGSTFLRY 462
                  ||.|::..|..:.     .:..||.:..::..|......  ::.|.|:.|.||::.|..
  Rat   502 ------FKELNSYEDFLDARFKTMRKDSLNSSHPISSSVQSSEQI--EEMFDSLSYFKGASLLLM 558

  Fly   463 LEDLFGGPTVFEPFLRDYLKKYAYKSIETKDFQSALYDYF-------IDTDKKDKLSAVDWDLWL 520
            |:. :....||:..:..||..::|.:|::.|    |:|.|       :|..|..|       .|.
  Rat   559 LKS-YLSEDVFQHAIILYLHNHSYAAIQSDD----LWDSFNEVTGKTLDVKKMMK-------TWT 611

  Fly   521 KSEGMPPV----------------IPNFDESLANVTKELASLWSSKSVAELADSAEIKTTISIHQ 569
            ..:|.|.|                .|:....:.:  .:.:.||.. .::.:.|........|: .
  Rat   612 LQKGFPLVTVQRKGTELLLQQERFFPSMQPEIQD--SDTSHLWHI-PISYVTDGRNYSEYRSV-S 672

  Fly   570 LIDFLGKLIESKDIVDLNEG----KINLLESTYNLKSSKNAEVRFRLNRL-----II----RARL 621
            |:|      :..|:::|.|.    |:|...:.|.:....:......:|:|     ::    ||.|
  Rat   673 LLD------KKSDVINLTEQVQWVKVNTNMTGYYIVHYAHDGWAALINQLKRNPYVLSDKDRANL 731

  Fly   622 IKRLDEILEFANSNFRMKF 640
            |..:.|:........:|.|
  Rat   732 INNIFELAGLGKVPLQMAF 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856
		leuko_A4_hydro	79..681	CDD:274120	153/645 (24%)
Lnpep	NP_001106874.1	Dileucine internalization motif. /evidence=ECO:0000255	53..54
		Dileucine internalization motif. /evidence=ECO:0000255	76..77
		Tankyrase binding. /evidence=ECO:0000250	96..101
		M1_APN-Q_like	176..612	CDD:341064	126/481 (26%)
		ERAP1_C	689..1009	CDD:463368	12/62 (19%)