Protein Alignment CG10602 and Lta4h

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_032543.2
• Gene: Lta4h / 16993
• MGIID: 96836
• Length: 611
• Species: Mus musculus
• Alignment Length: 622
• Identity: 275/622 - (44%)
• Similarity: 384/622 - (61%)
• Gaps: 34/622 - (5%)

  Fly    77 VVDPSSYSQP-DLITTEHSALNWKIDFAATKIQGSVLHRFKVLTANLDKILLDVRDINVTNATLL 140
            |.|..|.:.| .:..|:|..|...:|||...:.|:.....:....||..:.||.:|:.:....:
Mouse     4 VADTCSLASPASVCRTQHLHLRCSVDFARRTLTGTAALTVQSQEENLRSLTLDTKDLTIEKVVI- 67

  Fly   141 AGGSELPINFFISDAVDDIGQKLTLELPSGTAKG-SLNVRIDYETSSSASGLQWLNPTQTLGKEH 204
             .|.|  :.:.:.::....|..:.:.||...:|. .:.:.|.:|||..:|.||||.|.||.||:|
Mouse    68 -NGQE--VKYTLGESQGYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKQH 129

  Fly   205 PYMFSQCQAIHARSVIPCQDTPAVKFTYDATVEHPSELTALMSAL-----IDKKEPGKTL--FKQ 262
            ||:||||||||.|:::||||||:||.||.|.|..|.||.|||||:     .|.::|.:.:  |.|
Mouse   130 PYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGEAPDPEDPSRKIYRFNQ 194

  Fly   263 EVPIPAYLVAIAIGKLVSRPLGENSSVWAEEAIVDACAEEFSETATMLKTATELCGPYVWKQYDL 327
            .||||.||:|:.:|.|.||.:|..:.||:|:..|:..|.|||||.:|||.|.:|.|||||.||||
Mouse   195 RVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSANEFSETESMLKIAEDLGGPYVWGQYDL 259

  Fly   328 LVMPPSFPFGGMENPCLTFVTPTLLAGDKSLADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVF 392
            ||:|||||:||||||||||||||||||||||::|:||||:|||||||||||.::|||||||.||:
Mouse   260 LVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVY 324

  Fly   393 VESKIVGRMQGAKELDFKMLSNLTDLQECIRTQLNKTPELTKLVVDLSNCGPDDAFSSVPYIKGS 457
            :|..|.||:.|.|...|..|....:||..|:| ..::...|||||||.:..||.|:||:||.||.
Mouse   325 LERHICGRLFGEKFRHFHALGGWGELQNTIKT-FGESHPFTKLVVDLKDVDPDVAYSSIPYEKGF 388

  Fly   458 TFLRYLEDLFGGPTVFEPFLRDYLKKYAYKSIETKDFQSALYDYFIDTDKKDKLSAVDWDLWLKS 522
            ..|.|||.|.|||.||..||:.|:||::|:|:.|.|::|.||.:|  .||.|.|:.|||:.||.:
Mouse   389 ALLFYLEQLLGGPEVFLGFLKAYVKKFSYQSVTTDDWKSFLYSHF--KDKVDLLNQVDWNTWLYA 451

  Fly   523 EGMPPVIPNFDESLANVTKELASLW--------SSKSVAELADSAEIKTTISIHQLIDFLGKLIE 579
            .|:|||.||:|.:|.|....|:..|        ||.|:|:|.|       :|.|||.:||.::::
Mouse   452 PGLPPVKPNYDVTLTNACIALSQRWVTAKEEDLSSFSIADLKD-------LSSHQLNEFLAQVLQ 509

  Fly   580 SKDIVDLNEGKINLLESTYNLKSSKNAEVRFRLNRLIIRARLIKRLDEILEFANSNFRMKFCRPI 644
            .   ..|..|.|..::..||..:..|:|:|||..||.|:::..:.:...|:.|....||||.||:
Mouse   510 K---APLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEEAIPLALKMATEQGRMKFTRPL 571

  Fly   645 YRDLAGWPEAKPAAIRNFVNVKDQMMAVCSHTIEKDL 681
            ::|||.:.::...|:..:...|..|..|.:..:.:||
Mouse   572 FKDLAAFDKSHDQAVHTYQEHKASMHPVTAMLVGRDL 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856
		leuko_A4_hydro	79..681	CDD:274120	272/618 (44%)
Lta4h	NP_032543.2	leuko_A4_hydro	6..608	CDD:274120	272/618 (44%)