Protein Alignment CG10602 and erap2

DIOPT Version :10

• Sequence 1: NP_609916.5
• Gene: CG10602 / 35146
• FlyBaseID: FBgn0032721
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001116524.1
• Gene: erap2 / 100144556
• ZFINID: ZDB-GENE-080402-6
• Length: 931
• Species: Danio rerio
• Alignment Length: 724
• Identity: 160/724 - (22%)
• Similarity: 259/724 - (35%)
• Gaps: 208/724 - (28%)

  Fly    27 PFESAKL--------VKTHLLGLQKPIYHPMISTRGLCTSHKLLPIYQVQKRNMGRLGVVDPSSY 83
            ||..:|:        |..|||      .||.::|.....|.|:    ::..:|
Zfish    37 PFPWSKVRLPNYIVPVHYHLL------IHPNLTTLSFTGSVKI----EIDVKN------------ 79

  Fly    84 SQPDLITTEHSALNWKIDFAATKIQGSVLH--RFKVLTANLDKILLDVRDINVTNATLLAGGSEL 146
                       ..||           .|||  ..|:.||.    :||..:.:::..||..  .|.
Zfish    80 -----------NTNW-----------VVLHSKNLKIYTAT----VLDEHEAHLSEKTLSV--LEY 116

  Fly   147 PIN---FFISDAVDDIGQK--LTLELPSGTAKGSLN-VRIDYETSSSASGLQWLNPTQTLGKEHP 205
            |::   ...|..:...|:|  |.||..:..:.|... .:..|.|.|        ..|:.|...|
Zfish   117 PLHEQIAIFSPKILTSGEKYFLYLEFGAPLSDGFHGFYKSTYRTKS--------GETRVLASTH- 172

  Fly   206 YMFSQCQAIHARSVIPCQDTPAVKFTYDATVEH-PSELTALMSALIDKKEPGKTLFKQ----EVP 265
                 .:...||..:||.|.|..|..|...:.. ||.:......|....|....||:.    .|.
Zfish   173 -----FEPTSARMALPCFDEPVFKANYTVRIRRGPSHIALSNMPLEQTVEISNGLFEDHFEASVK 232

  Fly   266 IPAYLVAIAI--GKLVS--RPLGENSSVWAEEAIVDACAEEFSETATMLKTATELCGPYVWKQYD 326
            :.:||:|..:  .|.||  ...|.|.|::       |..|::.:|...|:.|..|...|  :||.
Zfish   233 MSSYLLAFIVCDFKSVSGLTATGINISIY-------AVPEKWHQTHYALEAALRLLEFY--EQYF 288

  Fly   327 LLVMP---------PSFPFGGMENPCLTFVTPTLLAGDKSLAD---------VVAHEIAHSWTGN 373
            .::.|         |.|..|.|||..||....|.|..|..::.         |:.||:||.|.||
Zfish   289 NILYPLPKLDLIAIPDFESGAMENWGLTTYRETSLLYDPDISSASDKLWVTMVIGHELAHQWFGN 353

  Fly   374 LVTNKNFEHFWLNEGFTVFVESKIVGRMQGAKELDFKMLSNLTDLQECI----RTQLNKTPELTK 434
            |||...:...||||||..::||..|..:....:::...|..      |.    |..||.:..::.
Zfish   354 LVTMDWWNDIWLNEGFARYMESVSVEAVYPELKVEDHFLDT------CFGAIGRDSLNSSRPISS 412

  Fly   435 LVVDLSNCGPDDAFSSVPYIKGSTFLRYLEDLFGGPTVFEPFLRD---------YLKKYAYKSIE 490
            |..:.:..  .:.|.:|.|.||:..|..|..          ||.|         ||::::|.:..
Zfish   413 LAENPTQI--KEMFDTVSYEKGACILHMLRH----------FLTDEGFQSGIIRYLRRFSYCNAR 465

  Fly   491 TKDFQSALYDYFIDTDKKDKLSAVDWDLWLKSEGMPPVIPNFDESLANVTKELASLWSSKSVAEL 555
            .:|    |:|..|.|..::..:|.:                :..|.|..||.     :.:...|.
Zfish   466 NED----LWDSLIKTCSEEDFAAGE----------------YCYSSAQATKN-----AYRFAGEH 505

  Fly   556 ADSAEIKTTISIHQLIDFL-----GK-------------LIESKDIVDLNEGKINLLESTYNLKS 602
            .|..::..|.::.:.|..:     ||             |.:......|.:|.:..:..||....
Zfish   506 VDLKKMMNTWTLQKGIPLVTVKRQGKKLHIGQERFLKIVLPDDPSWHSLQDGYLWHIPLTYKTSH 570

  Fly   603 SKNAEVRFRLNRLIIRARLIKRLDEILEFANSNFRMKFCRPIYRDLAGWPEAKPAAIRNFVNVKD 667
            |:: ||:    .::.:...:..|||.:::...|..|.....::.|..||            |...
Zfish   571 SEH-EVK----HILDKKSDVLLLDEHVDWVKLNTDMNGYYIVHYDEEGW------------NALT 618

  Fly   668 QMMAVCSHT 676
            :::.| :||
Zfish   619 ELLKV-NHT 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10602	NP_609916.5	Ribosomal_L13	15..>50	CDD:459856	9/30 (30%)
		leuko_A4_hydro	79..681	CDD:274120	147/664 (22%)
erap2	NP_001116524.1	M1_APN-Q_like	52..517	CDD:341064	134/580 (23%)
		ERAP1_C	594..913	CDD:463368	9/46 (20%)