Protein Alignment CG10600 and RSBN1

DIOPT Version :9

• Sequence 1: NP_001137839.1
• Gene: CG10600 / 35142
• FlyBaseID: FBgn0032717
• Length: 1406
• Species: Drosophila melanogaster
• Sequence 2: NP_060834.2
• Gene: RSBN1 / 54665
• HGNCID: 25642
• Length: 802
• Species: Homo sapiens
• Alignment Length: 971
• Identity: 295/971 - (30%)
• Similarity: 426/971 - (43%)
• Gaps: 297/971 - (30%)

  Fly    35 AVGASKQ-----RETPEKGVNKASAVENNNANARGNASPTTTSAQ----------REATTTITPV 84
            ||.|.::     :|.|..||:.........:::.|:.......:|          |.:.....|:
Human    61 AVAAQEEPDKEGKEKPHAGVSPRGVKRQRRSSSGGSQEKRGRPSQEPPLAPPHRRRRSRQHPGPL 125

  Fly    85 EPTAAATTTNGNTLPTQQQQQLQSGDGNANNPTTNARIMLAAAEEEQAVASSVATTAGAPTAATT 149
            .||.||.|..|...|                      ::|..........:..|..|..|..:|:
Human   126 PPTNAAPTVPGPVEP----------------------LLLPPPPPPSLAPAGPAVAAPLPAPSTS 168

  Fly   150 TATTTALADTTKTSTSTDEKTGKVKRNSQNTNPMSTNVICTPTHSPTPPTEERNHKRKKRDRERD 214
            ...|                          .:|::.:. ..|.|        :.||      ||.
Human   169 ALFT--------------------------FSPLTVSA-AGPKH--------KGHK------ERH 192

  Fly   215 EDKNRRSNNHNSSSKDRDKDRDRDKERDKERDRERE------RDRNRESSSKSSKEAEHK----S 269
            :..:.|..:.:.||...|.     |.:||:.:.||.      :...||:..::.|.....    .
Human   193 KHHHHRGPDGDPSSCGTDL-----KHKDKQENGERTGGVPLIKAPKRETPDENGKTQRADDFVLK 252

  Fly   270 SSSRSKEKYHRSDRDREREKERDREKIPSSSSSSSSHSNRRRSSDSSRSSQNSSFKSKDPGADPV 334
            ...:.|:|.||.|....|.|..::|
Human   253 KIKKKKKKKHREDMRGRRLKMYNKE---------------------------------------- 277

  Fly   335 LPQAVVAALEKQIKVEEVIKKEPVETKQEVDTEPTPVLSNLIKTEAEIKTESTEKPNKPLVNGEA 399
             .|.|.|.|.:       |.||                   |.|:.:|.:.|.       :|.|:
Human   278 -VQTVCAGLTR-------ISKE-------------------ILTQGQINSTSG-------LNKES 308

  Fly   400 IAKTRDEVSRQLNFGDKVSNSKLMPSPAPKSSSGSNSTASNHSSSQSSSSRKSYLSSSSSSSSSN 464
            ....:||...:||.|       :.....|:   |..:....|   |..|.|:::|.:.:..|:..
Human   309 FRYLKDEQLCRLNLG-------MQEYRVPQ---GVQTPFMTH---QEHSIRRNFLKTGTKFSNFI 360

  Fly   465 HHKSSSSSSSRHSSSTSRECSKCYKRSKIRRTSVGVQCLQHAPATGPWQTVQSLPPRPNRKPPAG 529
            |.:..|
Human   361 HEEHQS----------------------------------------------------------- 366

  Fly   530 LENLKYGCYFQVEQYPNGGASIVHLYQHEIDALSPDEMEELVDEFFEVCFAEDEQGYAHHVMGIV 594
                            ||||.::|.|..|:..|||.|||...:||..:.|:|:|:..|::.:.||
Human   367 ----------------NGGALVLHAYMDELSFLSPMEMERFSEEFLALTFSENEKNAAYYALAIV 415

  Fly   595 HDAARYLPDLLEHMAENYSTLTVKAGVLGRNSDIETCTMSQYNEQVVRNYCQGTFRYGPLHQISL 659
            |.||.||||.|::.|.|:....||..:||: .||||.|:|.::.||.|.||.||:|.||:.||||
Human   416 HGAAAYLPDFLDYFAFNFPNTPVKMEILGK-KDIETTTISNFHTQVNRTYCCGTYRAGPMRQISL 479

  Fly   660 VGKVHEEVGGYFPDLLGRIEMNPFLRKTMPWACNSILQTDPR-QSNDGPILWIRAGEQLVPTAEL 723
            ||.|.||||.|||:.|..:|.:|||:.|:||...|.|:...| ||:||||:|:|.|||::|||::
Human   480 VGAVDEEVGDYFPEFLDMLEESPFLKMTLPWGTLSSLRLQCRSQSDDGPIMWVRPGEQMIPTADM 544

  Fly   724 NSKTPLKRQRTRINELRNLQYLPRLSEARETMIEDRTKAHADHVGHGHERITTAAVGILKAVHCG 788
             .|:|.||:|: :||::|||||||.||.||.:.||||:|||||||.|.:..:|||||:||||..|
Human   545 -PKSPFKRRRS-MNEIKNLQYLPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFG 607

  Fly   789 QTYSQNRITKDVVAFAAQDFNTMVEMLQLDLHEPPISQCVQWIEDAKLNQLRREGVRYARIQLCD 853
            :...|.||||||:.|.|:||..:|:.|||||||||:||||||:::|||||:||||:|||||||||
Human   608 EWSDQPRITKDVICFHAEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCD 672

  Fly   854 NDIYFLPRNIIHQFRTVTAVTSVAWHLRLRQYYPGQEVI-NEKNNPVLAETPHYKEKQTILPNPI 917
            |||||:|||:||||:||:||.|:|||:||:||:|..|.. |.::|
Human   673 NDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHPVVEATQNTESN-------------------- 717

  Fly   918 SHDECGKKTPSKRAHDGRTKKKLIDLDGK------ERRSSESSIDEHPAAGSSSPSQNQEN 972
            |:.:|           |.|.|:.:::|.:      |...:.:.|.....|.||.|..::.|
Human   718 SNMDC-----------GLTGKRELEVDSQCVRIKTESEEACTEIQLLTTASSSFPPASELN 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10600	NP_001137839.1	None
RSBN1	NP_060834.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..244		40/246 (16%)
		Nuclear localization signal. /evidence=ECO:0000255	252..263		2/10 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158248
Domainoid	1	1.000	484	1.000	Domainoid score	I401
eggNOG	1	0.900	-	-		E1_KOG4425
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	484	1.000	Inparanoid score	I1457
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004037
OrthoInspector	1	1.000	-	-		otm40811
orthoMCL	1	0.900	-	-		OOG6_105705
Panther	1	1.100	-	-	LDO	PTHR13354
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2780
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.750