DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17597 and scp2a

DIOPT Version :9

Sequence 1:	NP_001286066.1	Gene:	CG17597 / 35140	FlyBaseID:	FBgn0032715	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_957159.1	Gene:	scp2a / 393839	ZFINID:	ZDB-GENE-040426-1846	Length:	538	Species:	Danio rerio

Alignment Length:	406	Identity:	283/406 - (69%)
Similarity:	337/406 - (83%)	Gaps:	3/406 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KTRVYVIGVGMTKFEKPGRRADACYPDFAKEAITKALQDAGIKFEEVQQAVAGYVYGDSTCGQRA 67
            :.||:|||||||||||||.| |..|||.||||..:||.|||||:..:|||..|||||||||||||
Zfish     5 RNRVFVIGVGMTKFEKPGAR-DIDYPDMAKEAGQRALADAGIKYSAIQQACVGYVYGDSTCGQRA 68

  Fly    68 IY-EVGMTGIPVYNVNNNCSTGSSALYLAKQIVESGNSECVLALGFEKMERGSLSAKYFDRANPM 131
            || .:|::|||:.||||||||||:||::.:|:::.|.::||||||||||||||||:||.||.|||
Zfish    69 IYHSLGLSGIPIINVNNNCSTGSTALFMGRQLIQGGLADCVLALGFEKMERGSLSSKYMDRTNPM 133

  Fly   132 ERHITEMSELTEIGAGPMAAQIFGNAGKEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRDEYT 196
            ::|:..|.....:.|.|.|.|:|||||:|||:|||||||||.|:||||||||.|||||||:|||:
Zfish   134 DKHMEVMINRYGLAAVPAAPQMFGNAGREHMEKYGTKPEHFAKVAWKNHKHSTNNPYSQFQDEYS 198

  Fly   197 LEQIMKSPQVVEGVLTKLQCCPTSDGSGAAILASEAFVRRHGLEKQAVEIVGMEMASDPASTFAD 261
            |||::.|.:|.| .||.|||||||||:|||:||||:||||:||||:|||||..||.:|.::||.:
Zfish   199 LEQVIDSRKVFE-FLTLLQCCPTSDGAGAAVLASESFVRRNGLEKKAVEIVAQEMVTDLSTTFEE 262

  Fly   262 KSLMKIAGTDMTRLATERLFAKSGYKPQDVQVVELHDCFSANELITYEALGLCGEGKAGEFIDAG 326
            .|.||:.|.||||||.||.:..:|.||.||.|:||||||||||||||||||||.||||||.||.|
Zfish   263 NSCMKMVGYDMTRLAAERCYDTAGVKPSDVDVIELHDCFSANELITYEALGLCPEGKAGELIDRG 327

  Fly   327 DNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAEKRQVPNAQLALQHNLGLGGAVV 391
            |||||||:|:|||||||||||||||||||||||||||||..|..||||.|:||||||:|||||||
Zfish   328 DNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRAEAGPRQVPGAKLALQHNIGLGGAVV 392

  Fly   392 VALYRLGFPGAAKAKL 407
            |.||::|||....:::
Zfish   393 VTLYKMGFPQETSSRI 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17597	NP_001286066.1	PRK08256	5..396	CDD:181327	279/391 (71%)
CG17597	NP_001286066.1	SCP-x_thiolase	9..395	CDD:238425	275/386 (71%)
scp2a	NP_957159.1	PRK08256	6..397	CDD:181327	279/392 (71%)
		nondecarbox_cond_enzymes	11..396	CDD:238422	275/386 (71%)
		SCP2	428..529	CDD:280250
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	283	1.000	Domainoid score	I1607
eggNOG	1	0.900	-	-		E1_KOG1406
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	692	1.000	Inparanoid score	I667
OMA	1	1.010	-	-		QHG61490
OrthoDB	1	1.010	-	-		D185465at33208
OrthoFinder	1	1.000	-	-		FOG0006286
OrthoInspector	1	1.000	-	-		otm26544
orthoMCL	1	0.900	-	-		OOG6_101329
Panther	1	1.100	-	-	O	PTHR24314
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3196
SonicParanoid	1	1.000	-	-		X4572
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870