DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17597 and Scp2

DIOPT Version :9

Sequence 1:	NP_001286066.1	Gene:	CG17597 / 35140	FlyBaseID:	FBgn0032715	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_612517.3	Gene:	Scp2 / 25541	RGDID:	3642	Length:	547	Species:	Rattus norvegicus

Alignment Length:	402	Identity:	267/402 - (66%)
Similarity:	322/402 - (80%)	Gaps:	2/402 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RVYVIGVGMTKFEKPGRRADACYPDFAKEAITKALQDAGIKFEEVQQAVAGYVYGDSTCGQRAIY 69
            ||:|:|||||||.|||......|||.||||..|||.||.|.:..|:||..|||||:|||||||||
  Rat    13 RVFVVGVGMTKFMKPGGENSRDYPDLAKEAGQKALADAQIPYSAVEQACVGYVYGESTCGQRAIY 77

  Fly    70 -EVGMTGIPVYNVNNNCSTGSSALYLAKQIVESGNSECVLALGFEKMERGSLSAKYFDRANPMER 133
             .:|:||||:.||||||||||:||::|:|:|:.|.:.|||||||||||:|||..||.||:||:|:
  Rat    78 HSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKMEKGSLGTKYSDRSNPLEK 142

  Fly   134 HITEMSELTEIGAGPMAAQIFGNAGKEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRDEYTLE 198
            ||..:.....:.|.|.|.|:||:||||||:.||||.|||.||.|||||||||||||||:|||:|:
  Rat   143 HIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAKIGWKNHKHSVNNPYSQFQDEYSLD 207

  Fly   199 QIMKSPQVVEGVLTKLQCCPTSDGSGAAILASEAFVRRHGLEKQAVEIVGMEMASDPASTFADKS 263
            :||||..|.: .||.|||||||||:.|||::||.||::|||:.:|||||..||.:|..|||.:||
  Rat   208 EIMKSRPVFD-FLTVLQCCPTSDGAAAAIVSSEEFVQKHGLQSKAVEIVAQEMVTDMPSTFEEKS 271

  Fly   264 LMKIAGTDMTRLATERLFAKSGYKPQDVQVVELHDCFSANELITYEALGLCGEGKAGEFIDAGDN 328
            ::|:.|.||::.|..:.:.|||..|.||.|:|||||||.|||:||||||||.||:.|..:|.|||
  Rat   272 VIKMVGYDMSKEAARKCYEKSGLGPSDVDVIELHDCFSTNELLTYEALGLCPEGQGGALVDRGDN 336

  Fly   329 TYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAEKRQVPNAQLALQHNLGLGGAVVVA 393
            |||||:|:||||||||||||||||||||||||||||||.|.|||||.|::|||||||||||.||.
  Rat   337 TYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGLGGAAVVT 401

  Fly   394 LYRLGFPGAAKA 405
            |||:|||.||.:
  Rat   402 LYRMGFPEAASS 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17597	NP_001286066.1	PRK08256	5..396	CDD:181327	260/391 (66%)
CG17597	NP_001286066.1	SCP-x_thiolase	9..395	CDD:238425	256/386 (66%)
Scp2	NP_612517.3	PRK08256	12..404	CDD:181327	260/391 (66%)
		SCP2	452..538	CDD:396566
		Microbody targeting signal. /evidence=ECO:0000255	545..547
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	263	1.000	Domainoid score	I1862
eggNOG	1	0.900	-	-		E1_KOG1406
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	663	1.000	Inparanoid score	I725
OMA	1	1.010	-	-		QHG61490
OrthoDB	1	1.010	-	-		D185465at33208
OrthoFinder	1	1.000	-	-		FOG0006286
OrthoInspector	1	1.000	-	-		otm45186
orthoMCL	1	0.900	-	-		OOG6_101329
Panther	1	1.100	-	-	O	PTHR24314
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4572
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.880