DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt2a6

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001138283.1	Gene:	ugt2a6 / 797211	ZFINID:	ZDB-GENE-081104-3	Length:	529	Species:	Danio rerio

Alignment Length:	535	Identity:	146/535 - (27%)
Similarity:	256/535 - (47%)	Gaps:	88/535 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNGYKD----HLLPPSTLTDTISLEDFERPYSFL 95
            ||:....|::..|.:..|||.|:........|:..|:    |:.       .:::|.....|.::
Zfish    31 SHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHTQKERFEYHVF-------KVNMEKEVVDYLWI 88

  Fly    96 FHYVEFFILHKMGREDCNT---TL-----------HSRALTEILKNPPGYYDVILLEQFN----- 141
             |:.|.::     .|..:|   ||           ||..|.:      |.:||.||:...
Zfish    89 -HFHELWM-----NETISTYEKTLEVWQLMSLFRAHSEELVK------GLFDVGLLKTLRDSNYD 141

  Fly   142 ---TDCAM----------SVAHVFQAPVIGMSS----CALMPWHYERFGAPLIP-SYI-SALFQG 187
               :|..|          ::.||....:...|:    |..||          :| ||: :|:.||
Zfish   142 VLFSDLTMPFSDLMAQKLNIPHVLSMRISFASALERLCGQMP----------VPQSYVPAAVAQG 196

  Fly   188 Q-SQEMSFAGRLGN---WITVHSLNLLYKMFTVPAGNALIRQRFGPGLPSTE-DLVRNTSLMLVN 247
            . :..|||..|:.|   :||..::..|...||.....|.|     .|.|:|. :.:..|.:.|:.
Zfish   197 HLTDRMSFTERVENMLLYITHTAMFQLTTKFTFDHIYAEI-----SGEPTTMCETIGKTDIWLIR 256

  Fly   248 QHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILDNA-PKGVILISWGSQLKACSLSAARRD 311
            .::....|:|.|||...|||:...|.|||..:|::.:.:: ..|:::.|.||.:|  :|:..:.:
Zfish   257 TYWDFEYPRPFPPNFKFVGGLQCKPAKPLAKELEEFVQSSGDHGIVVFSLGSMIK--NLTVQKAN 319

  Fly   312 GIVKAIGRLEQEVIWKYENDTLPNKPPNLHIRKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSA 376
            .|..|:|::.|:|:|:|...|.....||..|..|:||.|:|.||..|.|::|||..|..||:...
Zfish   320 TIAAALGQISQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHG 384

  Fly   377 VPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKAL-DPSFKARAKEVASSYNNR 440
            ||:||:|::|||..|:..|..:|.|:.|:...|:...:.:||...| :||:|.....::..::::
Zfish   385 VPMVGLPLFGDQPDNLMHLKSKGAAVVLDFFTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQ 449

  Fly   441 IQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYS-VVALSLLLPVITLLGLIRMFK 504
            ...||:.|::|:|.|...|||...:..|..||.:.|:.|||.: :::::.|:..:.:.....:|:
Zfish   450 PMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSITALITFLWVKACCFLFR 514

  Fly   505 R--REPKGDRKLKRK 517
            |  |:.:.:||.|::
Zfish   515 RCVRKTRPERKSKKE 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	129/473 (27%)
ugt2a6	NP_001138283.1	UDPGT	21..519	CDD:278624	142/523 (27%)
ugt2a6	NP_001138283.1	egt	<254..485	CDD:223071	78/232 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584376
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930