DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt5b4

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001074161.1	Gene:	ugt5b4 / 791210	ZFINID:	ZDB-GENE-070112-2332	Length:	531	Species:	Danio rerio

Alignment Length:	571	Identity:	139/571 - (24%)
Similarity:	244/571 - (42%)	Gaps:	107/571 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WKV-FCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNG 68
            |.| .|||.:::.|..|.::.:   ||... ||:...:.::..|...||::.||
Zfish    10 WPVTLCLLLVMAPVVESGNVLV---FPVDG-SHWVNMNILVEALHAKGHNITVI----------- 59

  Fly    69 YKDHLLPPSTLTDTISLEDFERPYSFLFHYVEFFILHKMG-REDCNTTLHSRALTEILKNPPGY- 131
                     .::|:..:::|..      ||....:....| .||...|..||.:| ||::...:
Zfish    60 ---------RMSDSWYIKEFSP------HYTSITLKSSGGFSEDILETFASRLIT-ILRDGSTWG 108

  Fly   132 ----------------------------------------YDVILLEQFNTDCAM----SVAHVF 152
                                                    ||:.|     ||.||    .:.:..
Zfish   109 RLKLEMEMWQSSLKIMETEREMIINMIEDQQLIDSLKKTKYDLFL-----TDPAMYGGVILGNYL 168

  Fly   153 QAPVIGMSSCALM-PWHYERFGAPLIPSYISALFQGQSQEMSFAGRLGNWITVHSLNLLYKMFTV 216
            :.|::.....|:. ..|:....:||  ||:..........|||..|:.|.:..............
Zfish   169 KLPIVYNVRWAIFGEGHFVIAPSPL--SYVPVAMLELPDRMSFLERVKNVVMYIITETQIAFLIA 231

  Fly   217 PAGNALIRQRFGPGLPSTEDLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQ 281
            |..|.|..:..|||: :..:||:...|.|....|....|:|..||::.:.|....|.||||.||:
Zfish   232 PTYNVLCERFIGPGV-NLFNLVQGADLWLHRADFVFEYPRPTMPNIVYMAGFQCKPSKPLPKDLE 295

  Fly   282 KILDNA-PKGVILISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWKYE--------NDTLPNKP 337
            ..:.:: ..|||::|.|:.:.......|  :.|.:|...|.|::||:|:        |:||
Zfish   296 DFVQSSGDHGVIVMSLGTIIGQLPDDVA--EAIAEAFAELPQKIIWRYKGKRPSALGNNTL---- 354

  Fly   338 PNLHIRKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMAL 402
                |..|:||.|:|.||..:.|::|||..|..||:...|||:|..:..||..|::.:..||.|.
Zfish   355 ----IMDWMPQNDLLGHPKTRAFVAHGGTNGVQEAIYHGVPIIGFGLIFDQPDNLSKMRVRGAAK 415

  Fly   403 QLELKKLDENTVYEALTKAL-DPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQP 466
            .::...:|:.:..:.:.:.| |||::...:.::..:.:....||:.||:|:|.|...|||...:.
Zfish   416 NVDFATMDKESFLKTVKEVLYDPSYRENMQRLSRLHKDVPVKPLDNAIFWIEFVMRHKGAAHLRT 480

  Fly   467 SAVHLSRFVYYSLDVYSVVALSLLLPVITLLGLIRMFKRREPKGDRKLKRK 517
            .:..:..:.|:|:||..|:..::.|.::::..:||.|..:......|:||:
Zfish   481 ESYKMPWYSYHSVDVILVLISAVSLIILSIYAVIRYFCCKICMRKTKIKRQ 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	124/512 (24%)
ugt5b4	NP_001074161.1	egt	12..501	CDD:223071	131/537 (24%)
ugt5b4	NP_001074161.1	UDPGT	27..531	CDD:278624	131/552 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584290
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.740