Protein Alignment Ugt36E1 and UGT2B15

DIOPT Version :9

• Sequence 1: NP_609911.1
• Gene: Ugt36E1 / 35139
• FlyBaseID: FBgn0027070
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001067.2
• Gene: UGT2B15 / 7366
• HGNCID: 12546
• Length: 530
• Species: Homo sapiens
• Alignment Length: 555
• Identity: 143/555 - (25%)
• Similarity: 257/555 - (46%)
• Gaps: 73/555 - (13%)

  Fly     5 WKVFCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNGY 69
            |....||..||....|.|...:.::| ...||:.....|:..|.:.||.|.|::.
Human     5 WTSVFLLIQLSCYFSSGSCGKVLVWP-TEYSHWINMKTILEELVQRGHEVTVLTS---------- 58

  Fly    70 KDHLLPPSTL-----TDTISLEDFERPYSFLFHYVEFFILHKMGR-------------------- 109
                 ..|||     :..|.||.:  |.|...:|:|..:|..:.|
Human    59 -----SASTLVNASKSSAIKLEVY--PTSLTKNYLEDSLLKILDRWIYGVSKNTFWSYFSQLQEL 116

  Fly   110 ---------EDCNTTLHSRALTEILKNPPGYYDVILLEQFNTDCAMSVAHVFQAPVIGMSSCALM 165
                     :.|...:.::.|  ::|.....:||||.:..| .|...:|.:|..|.: .|....:
Human   117 CWEYYDYSNKLCKDAVLNKKL--MMKLQESKFDVILADALN-PCGELLAELFNIPFL-YSLRFSV 177

  Fly   166 PWHYERFGAPLI--PSYISALFQGQSQEMSFAGRLGNWITVHSLNLLYKMFTVPAGNALIRQRFG 228
            .:.:|:.|...:  |||:..:....|.:|.|..|:.|.|.:...:..::::.:...:....:..
Human   178 GYTFEKNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIHMLYFDFWFQIYDLKKWDQFYSEVL- 241

  Fly   229 PGLPST-EDLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILDNA-PKGV 291
             |.|:| .:.:....:.|:..::....|:|..|||..|||:|..|.||||.::::.:.:: ..|:
Human   242 -GRPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGENGI 305

  Fly   292 ILISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWKYENDTLPNKPPNLHIRKWLPQRDILAHPN 356
            ::.|.||.:...|..:|..  |..|:.::.|:|:|:::.........|..:.|||||.|:|.||.
Human   306 VVFSLGSMISNMSEESANM--IASALAQIPQKVLWRFDGKKPNTLGSNTRLYKWLPQNDLLGHPK 368

  Fly   357 LKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKA 421
            .|.|::|||..|..||:...:|:||:|::.||..|||.:..:|.||.::::.:....:..||...
Human   369 TKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSV 433

  Fly   422 L-DPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSVV 485
            : ||.:|....:::..::::...||:.|::|:|.|...|||...:.:|.:|:...|:||||.:.
Human   434 INDPVYKENVMKLSRIHHDQPMKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDVIAF- 497

  Fly   486 ALSLLLPVITLLGLIRMF----KRREPKGDRKLKR 516
               ||..|.|::.:|..|    .|:..|..:|.||
Human   498 ---LLACVATVIFIITKFCLFCFRKLAKKGKKKKR 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	122/493 (25%)
UGT2B15	NP_001067.2	egt	8..508	CDD:223071	135/529 (26%)
		UDPGT	24..518	CDD:278624	131/523 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150103
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.740