DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36E1 and ugt5b6

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001035435.1	Gene:	ugt5b6 / 678597	ZFINID:	ZDB-GENE-060421-3572	Length:	531	Species:	Danio rerio

Alignment Length:	551	Identity:	136/551 - (24%)
Similarity:	241/551 - (43%)	Gaps:	104/551 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNGYKDHLL 74
            |..||..|....|.::| :|| ..:||:.....::..|...||::.|:
Zfish    14 LTILLVTVPVVQSGKVL-VFP-VDVSHWVNMKILVEALHAKGHNITVM----------------- 59

  Fly    75 PPSTLTDTISLEDFERPYS---------FLFHYVEFF------ILH--------KMGREDCNTT- 115
               .:.|:..:::|...|:         |...::|.|      ||.        |:..|...||
Zfish    60 ---RMADSWYIKEFSPHYTSINLKSAGGFGEDFLETFASRLMAILREGSIWGRLKLEAEVWQTTW 121

  Fly   116 -------------LHSRALTEILKNPPGYYDVILLEQFNTD----CAMSVAHVFQAPVIGMSSCA 163
                         :..:.|.::||:  ..|||||     ||    ..:.:.|..:.|::..:.
Zfish   122 KMIETESVMIVNMIEDQKLMQLLKD--AKYDVIL-----TDPTIFGGVILGHYLKLPMVYNAR-- 177

  Fly   164 LMPW------HYERFGAPLIPSYISALFQGQSQEMSFAGRLGNWITVHSLNLLYKMFTVPAGNAL 222
               |      |:....:||  ||:.......|..|||..|:.|.:....:.:...:...|..:||
Zfish   178 ---WTIYSEAHFAIAPSPL--SYVPFPSLELSDRMSFLERVCNVVMYTIIEIGAALVIAPINDAL 237

  Fly   223 IRQRFGPGLPSTEDLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILDNA 287
            ..:..||| .|...||:...|.|....|....|:|..||::.:.|....|.||||.||:..:.::
Zfish   238 AERFIGPG-TSYLSLVQGADLWLHRVDFVFEYPRPTMPNIVYMAGFQCKPSKPLPQDLEDFVQSS 301

  Fly   288 -PKGVILISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWKYE--------NDTLPNKPPNLHIR 343
             ..|||::|.|:.:.......|  :.|.:|...|.|::||:|:        |:||        :.
Zfish   302 GDHGVIIMSLGTLIGQLPEDVA--EAIAEAFAELPQKIIWRYKGKRPSALGNNTL--------VM 356

  Fly   344 KWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKK 408
            .|:||.|:|.|...:.|::|||..|..||:...|||:|..:..||..|::.:..||.|..::...
Zfish   357 DWMPQNDLLGHSKTRAFVAHGGTNGVQEAIYHGVPIIGFGLIFDQPDNLSKMRVRGAAKNVDFAT 421

  Fly   409 LDENTVYEALTKAL-DPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLS 472
            :|:.:..:.:.:.| :|:::...:.::..:.:....||:.||:|:|.|...|||...:..:..:.
Zfish   422 MDKESFLKTVKEVLYNPTYRENMQRLSRLHKDVPVKPLDNAIFWIEFVMRHKGAAHLRTESNKMP 486

  Fly   473 RFVYYSLDVYSVVALSLLLPVITLLGLIRMF 503
            .:.|:|:||..|:..::.|.::|:..:||.|
Zfish   487 WYSYHSVDVILVLISAVSLIILTIFAVIRYF 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	123/506 (24%)
ugt5b6	NP_001035435.1	egt	5..501	CDD:223071	131/533 (25%)
ugt5b6	NP_001035435.1	UDPGT	27..529	CDD:278624	131/538 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000