Protein Alignment Ugt36E1 and Ugt1a8

DIOPT Version :10

• Sequence 1: NP_609911.1
• Gene: Ugt36E1 / 35139
• FlyBaseID: FBgn0027070
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001365304.1
• Gene: Ugt1a8 / 613123
• MGIID: 3576090
• Length: 530
• Species: Mus musculus
• Alignment Length: 519
• Identity: 139/519 - (26%)
• Similarity: 242/519 - (46%)
• Gaps: 60/519 - (11%)

  Fly     9 CLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNGYKDHL 73
            |||....|   :.:.|:| :.|... ||:.....|:..|:..||.|.|:.|        ....||
Mouse    15 CLLLAFGL---AQAGRLL-VVPMDG-SHWFSMKMIVEKLSHRGHEVVVVIP--------EVSWHL 66

  Fly    74 -----LPPSTLTDTISLEDFERPYSFLFH-------YVEFFILHKMGR-------EDCNTTLHSR 119
                 ....|.:.:.:|||....::|..|       ...|.:|...|:       ..|.:..:.:
Mouse    67 GKSQNFTVKTYSVSYTLEDLSHHFNFFAHKQWENREVGMFSLLKHSGKGFFQVLFSHCRSLFNDK 131

  Fly   120 ALTEILKNPPGYYDVILLEQFNTDCAMSVAHVFQAPVIGMSS---CALMPWHYERFGA--PLIPS 179
            .|.|.||...  :|.:.|:.|:. |.:::|..|..|.:..|.   |     ||...||  |..||
Mouse   132 KLVEYLKQRS--FDAVFLDPFDV-CGLTIAKYFSLPSVVFSGGIFC-----HYLDEGAQCPSPPS 188

  Fly   180 YISALFQGQSQEMSFAGRLGNWITVHSLNLLYKMF---TVPAGNALIRQRFGPGLPST-EDLVRN 240
            |:..:....:..|:|..|:.|:.:..........|   .:...:.:::      .|.| .||..:
Mouse   189 YVPRILSKFADTMTFKERVWNYFSYMKERAFCPYFFKTAIEIASEVLQ------TPVTMTDLFSS 247

  Fly   241 TSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILD-NAPKGVILISWGSQLKACS 304
            .|:.:....|.|..|:|:.||::.:||::..|.|||..:.:..:: :...|:::.|.||.:....
Mouse   248 VSIWMFRTDFVLEFPRPVMPNMVYIGGINCHPGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIP 312

  Fly   305 LSAARRDGIVKAIGRLEQEVIWKYENDTLPNKPPNLHIRKWLPQRDILAHPNLKVFMSHGGLMGT 369
            ...|..  |.:|:||:.|.|:|:|......|...|..:.|||||.|:|.||..:.|::|.|..|.
Mouse   313 EKKAME--IAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGI 375

  Fly   370 TEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKAL-DPSFKARAKEV 433
            .|.:.:.||:|.:|::|||..|...:..||..:.|.:.::..:.:..||...: :.|:|.....:
Mouse   376 YEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRL 440

  Fly   434 ASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSVVALSLLLPVITLL 497
            :|.:.:|...||:.|::|||:|...||||..:|:|..|:.:.|:||||...: |:::|.|:.::
Mouse   441 SSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFL-LAIVLTVVFIV 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	GT1_Gtf-like	23..453	CDD:340817	117/459 (25%)
Ugt1a8	NP_001365304.1	UDPGT	26..521	CDD:278624	135/505 (27%)