DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36E1 and ugt5g2

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001186305.1	Gene:	ugt5g2 / 556049	ZFINID:	ZDB-GENE-081028-66	Length:	534	Species:	Danio rerio

Alignment Length:	554	Identity:	162/554 - (29%)
Similarity:	262/554 - (47%)	Gaps:	72/554 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCGCWKVFCLLA--LLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDK 63
            |.||..:..|..  ||||.:..::.:|| :||... ||:.....:::.|...||.:.||. .||.
Zfish     1 MQGCMSLVFLWTSLLLSLPSGYNADKIL-VFPIDG-SHWVNMEVLVKKLQSRGHELSVIR-LEDS 62

  Fly    64 DPPNGYKDHLLPPSTLTDT-----ISLEDFERP-------------YSFLFHYVEFFILHKMGRE 110
            ....|...:.   |::|.|     |.|:.||..             ...|....||..:.|:| .
Zfish    63 WFIKGNSPYY---SSITVTLKKKFIDLDLFETAVKKILDARRDGPIMGVLAQMSEFIGILKVG-H 123

  Fly   111 DCNTTLHSRALTEILKN-------PPGYYDVILLEQFNTDCAMS----VAHVFQAPVI-GMSSCA 163
            ..|..:    ||.:|:|       ....||::|     ||.||.    :||....|:: .:...:
Zfish   124 GANIAM----LTSMLENKVLMSQIKMANYDLML-----TDPAMPGGVILAHYLHLPMVYNVRWMS 179

  Fly   164 LMPWHYERFGAPLIPSYISALFQGQSQEMSFAGRLGNWITVHSLNLLY-KMFTVPAGNALIRQRF 227
            ....|:....:|:  |::.....|.:..|....|..|::. :.|||:. :...:|...:|:...|
Zfish   180 FGEGHFSIAPSPI--SFVPVPGSGLTDRMGLLERSRNFLH-YGLNLIQERWMVIPMYTSLLLNHF 241

  Fly   228 GPGLPSTEDLV---RNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILDNA-P 288
            .||    .||:   |:..|.||...|....|:|..||::.:||....|.||||:||::.:.:: .
Zfish   242 PPG----TDLLTMQRSAELWLVRADFVFEFPRPSMPNLVYIGGFQCRPAKPLPADLEEFMQSSGD 302

  Fly   289 KGVILISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWKY---ENDTLPNKPPNLHIRKWLPQRD 350
            .||:::|.|:.:  ..|.....:.|..|..::.|:|||::   ...||.|   |..:.:||||.|
Zfish   303 HGVVVMSLGTLI--AGLPKEVMEAIASAFAQIPQKVIWRFIGQRPSTLGN---NTLLIQWLPQND 362

  Fly   351 ILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVY 415
            :|.||..:.|::|||..|..||:...||::|:|:..||..||..|..||.|..|:..........
Zfish   363 LLGHPKTRAFVAHGGTNGLYEAIYHGVPVLGLPLLFDQLDNIVRLQARGGARMLDAATCSTKEFL 427

  Fly   416 EALTKALD-PSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSL 479
            .|||..|: |:::...:::::.:.:|...||:.|::|:|.|...||||..:..|.::|.|.||.|
Zfish   428 VALTDILENPTYRQNMQKLSNLHRDRPLHPLDKAVYWIEFVLRNKGAPHLRAEAYNVSEFSYYCL 492

  Fly   480 DVYSVVALSLLLPVITLLGLIRMFKRREPKGDRK 513
            |   ||||.|.:.:.||.|:..:.|||..:.:.|
Zfish   493 D---VVALVLFMLLGTLGGVYTICKRRPKRQENK 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	138/497 (28%)
ugt5g2	NP_001186305.1	egt	3..507	CDD:223071	155/534 (29%)
ugt5g2	NP_001186305.1	UDPGT	25..513	CDD:278624	150/518 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584310
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.740