DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36E1 and ugt2a1

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	XP_031759199.1	Gene:	ugt2a1 / 447975	XenbaseID:	XB-GENE-954008	Length:	735	Species:	Xenopus tropicalis

Alignment Length:	513	Identity:	134/513 - (26%)
Similarity:	251/513 - (48%)	Gaps:	69/513 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SHFKFFHPIMRGLAEAGHSVDVI----SPFEDKDPPNGYKDHLLPPSTLTDT-ISLE-DFERPYS 93
            ||:.....|:..||..||.|..:    :...|.:.|:..|..:.|.:...:| ::|: ||...:.
Frog   240 SHWLNLRLILEELAHKGHEVTALVHSANMLIDHNLPSALKAEVFPVAFTKETFLTLQRDFFNFWI 304

  Fly    94 FLFHYVEFFILH-----------KMGREDCNTTLHSRALTEILKNPPGYYDVILLEQFNTDCAMS 147
            :..|.:.::.|:           |:.|:.|:..|.::.|...|:|..  :|:::.:.. ..|...
Frog   305 YGVHNMSYWELYEHLKVAVASSLKLQRDTCDGVLKNKELMYKLQNQK--FDIVVADPV-APCGEL 366

  Fly   148 VAHVFQAPVI-------GMS---SCALMPWHYERFGAPLIPSYISALFQGQSQEMSFAGRLGNWI 202
            :|.....|.:       |.|   .|..:|       :|.  ||:.......|.:|||..||.|.:
Frog   367 IAESLGVPFVYSFRFSMGNSLERLCGQLP-------SPF--SYVPGAMTAFSDKMSFGQRLANTV 422

  Fly   203 TVHSLNLLYKMFTVPAGNALIRQRFGP-------GLPSTE-DLVRNTSLMLVNQHFSLSGPKPLP 259
            .....:|::         :|:.|:...       |.|:.. :::....:.|:..::....|:|:.
Frog   423 LYAFQDLIF---------SLVFQKNWDNYYSEILGRPAKVCEIMGKAEIWLIRTYWDFEYPRPIL 478

  Fly   260 PNVIEVGGVHISPPKPLPSDLQKILDNAPK-GVILISWGSQLKACSLSAARRDGIVKAIGRLEQE 323
            ||...|||:|.:|.||||.:::|:::::.: |:::.|.||.:|  :.|..|.:.|..|:.:|.|:
Frog   479 PNFKFVGGLHCAPAKPLPEEIEKVVESSGEHGIVVFSMGSMIK--NFSNERTNIIAAALSQLPQK 541

  Fly   324 VIWKYENDTLPNKP----PNLHIRKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPI 384
            |:|:|..    .||    .|.....|:||.|:|.||..|.|::|||..|..||:...|||||:|:
Frog   542 VLWRYSG----KKPDALGENTITYDWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPIVGIPL 602

  Fly   385 YGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKAL-DPSFKARAKEVASSYNNRIQGPLETA 448
            :.:|..||..:..:|||:.|:..|:....:.:|:...: :|::|..|..::..::::...||::|
Frog   603 FAEQPDNIVHMKSKGMAIMLDFNKMGTQDLLDAVNTVINNPTYKENAMRLSRIHHDQPVKPLDSA 667

  Fly   449 IWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSVVALSL-LLPVITLLGLIRMFKR 505
            ::|:|.|...|||...:|::..|:.:.|:.|||...:.:.| |...||:..|...:|:
Frog   668 VFWIEFVMRHKGAKHLRPASHELTWYQYHCLDVIGFMFVCLFLFFYITITFLTFCYKK 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	119/465 (26%)
ugt2a1	XP_031759199.1	UDPGT	238..733	CDD:278624	134/513 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm9349
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000