DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and Ugt36A1

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001285591.1	Gene:	Ugt36A1 / 44058	FlyBaseID:	FBgn0015663	Length:	537	Species:	Drosophila melanogaster

Alignment Length:	534	Identity:	186/534 - (34%)
Similarity:	291/534 - (54%)	Gaps:	32/534 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VFCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNG--- 68
            :..||.:|.:.....:..||.::||...||||...||:..||..||.:.|||..  |:|..|
  Fly    11 IIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYV--KNPQAGAYP 73

  Fly    69 -YKDHLL------PPSTLTDTISLEDFERPYSFLFHYVEFFILHKMGREDCN---TTLHSRALTE 123
             |::.|:      ..||..:.:.|.:.....|......|:..||:.|::.|.   .:.|.....|
  Fly    74 NYEELLISAPGEDQSSTTINLVPLTEHTPTRSLGVLIREYVDLHEEGQKTCEHLFASGHIERAIE 138

  Fly   124 ILKNPPGYYDVILLEQFNTDCAMSVAHVFQAPVIGMSSCALMPWHYERFGAPLIPSYISALFQGQ 188
            ..:|.|  ||::|.|.||:||.:::|.:...|:||:|:|||||::|:|...|..|::|.:.|.|.
  Fly   139 RHRNKP--YDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYYDRIDLPDTPAFIQSEFVGF 201

  Fly   189 SQEMSFAGRLGNWITVHSLNLLYKMFTVPAGNALIRQRFGPGLPSTEDLVRNTSLMLVNQHFSLS 253
            :.::::..||.|::....|..|||..:..|.|.|:|:..|..:...|.....|:.:..|||:||.
  Fly   202 AGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGVEVDVEEVARTQTAFIFGNQHYSLM 266

  Fly   254 GPKPLPPNVIEVGGVHIS--PPKPLPSDLQKILDNAPKGVILISWGSQLKACSLSAARRDGIVKA 316
            |.:|.....:|:|||||:  ..:.||.::...|:.:.:|||.|||||.::|.|:...:...|::.
  Fly   267 GSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQSAEGVIFISWGSMVRASSIDEDKLSAILEV 331

  Fly   317 IGRLEQEVIWKYENDTLPNKPPNLHI-RKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIV 380
            :.....::|||:|.|..|:...:..: .||.||..:|.||.:|:|.|||||:||||:|....|::
  Fly   332 LKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALLCHPKVKLFWSHGGLLGTTESVHCGKPLL 396

  Fly   381 GVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKALDPSFKARAKEVASSYNNRIQGPL 445
            ..||||||.||..::..|||.|:|:.:.:....:.:||.:....|:..|:.||:..:|.|.|.||
  Fly   397 VTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKALAELSKNSYAQRSLEVSKVFNERQQTPL 461

  Fly   446 ETAIWWVEHVAETK--GAPLTQPSAVHLSRFVYYSLDVYSVVALSLLLPVITLLGLIRMFKRREP 508
            |:|||.||||....  .|.|.|...:.|:.|||:|||   .||| :|||:|.|:.::....:|.|
  Fly   462 ESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSLD---SVAL-ILLPLILLILVLCYLCKRNP 522

  Fly   509 ------KGDRKLKR 516
                  |..:|.||
  Fly   523 SKLAHKKVGKKPKR 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	162/470 (34%)
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	162/467 (35%)
Ugt36A1	NP_001285591.1	UDPGT	38..501	CDD:278624	165/469 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471433
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BKDN
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D100631at6960
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.900