DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and Ugt303B1

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	517	Identity:	158/517 - (30%)
Similarity:	267/517 - (51%)	Gaps:	20/517 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 CWKVFCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNG 68
            ||....|..||.... :.:..|||:||:..||.|....|::|.||..||:|.:|:|....:...|
  Fly     6 CWLTLSLCLLLQHDR-AQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPIGMPNDIEG 69

  Fly    69 YKDHLLPPSTLTDTI-SLEDFERPYSFLFH-YVEFFILHKMGREDCNTTLHSRALTEILKNPPGY 131
            .:.  :..:.|.:.| .:.:.::...|:.: :.|..:..|......|..|....:..:|.:....
  Fly    70 VRH--IRVAQLNERIKEMLESDQVLDFMINKWTESALTAKALFNASNDILSDPGVQRMLHDKSES 132

  Fly   132 YDVILLEQFNTDCAMSVAHVFQAPVIGMSSCALMPWH-YERFG--APLIPSYISALFQGQSQEMS 193
            :|:|::|..:.|....:...:.|.::|:||..: .|| ||..|  ||.|...||.:  |.|.|.|
  Fly   133 FDLIIMEPSSLDALYGLVEFYNATLMGLSSIRI-NWHTYELAGNPAPSIYEPISPV--GFSLETS 194

  Fly   194 FAGRLGNWITVHSLNLLYKMFTVPAGNALIRQRFGPGLPSTEDLVRNTSLMLVNQHFSLSGPKPL 258
            ...|:.|||.:....|:..:...||...|.::.||.......:|....||||:|.|:|:...:..
  Fly   195 LFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYSAQKMNELRSRFSLMLINSHYSMGKVRAN 259

  Fly   259 PPNVIEVGGVHIS-PPKPLPSDLQKILDNAPKGVILISWGSQLKACSLSAARRDGIVKAIGRLEQ 322
            .||:|||||:|:| ||:|...:|||.||.|..|||..|.|:.:....|....::.:::....|.:
  Fly   260 APNIIEVGGLHLSEPPEPSDEELQKFLDKADHGVIYFSMGNDILIKFLPENIQELLLQTFATLNE 324

  Fly   323 EVIWKYENDTLPNKPPNLHIRKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGD 387
            .:|||.|...:|:|..|:::.:..|||.||.|||:::|:::|||:...|||.|.||::|:|::.|
  Fly   325 SIIWKSELLYMPDKSDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFD 389

  Fly   388 QSLNIAALVQRGMALQLELKKLDENTVYEALTKAL-DPSFKARAKEVASSYNNRIQGPLETAIWW 451
            |..|:..:...|||..:::..|:::|:.|.:...| :.|:..:|||::..:.:|...||:||:||
  Fly   390 QFGNMRWVQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWW 454

  Fly   452 VEHVAETKGAPLTQPSAVHLSRFVYYSLDV-------YSVVALSLLLPVITLLGLIRMFKRR 506
            .|:....:.....:.:...:....||.:|.       :.:||.||:..|.||....|:..||
  Fly   455 TEYALRNRNITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLVYTLFLKYRIRLRR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	145/462 (31%)
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	140/445 (31%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	142/474 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454619
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.890