DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt-39

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_504816.2	Gene:	ugt-39 / 3564933	WormBaseID:	WBGene00017329	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	543	Identity:	129/543 - (23%)
Similarity:	213/543 - (39%)	Gaps:	81/543 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VFCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISP-----FEDKDPP 66
            :|.|......|:..:.|....||.|   ||.|||..|...|.:|||:|...:|     :.:....
Worm     4 LFILFLFFGNVSSFNFLVFCPLFAH---SHSKFFATIADSLTDAGHNVTFFTPTIVEKYRNVSYT 65

  Fly    67 NGYKD--HLLPPSTLT---DTISLEDFERPYSFLFHYVEFF----ILHKMGREDCNTTLHSRA-- 120
            ...||  |:.|...|.   :.:|..||.|.::......|..    |..||..|. .|.:....
Worm    66 KSTKDVVHMKPSKKLKEYGEQMSTGDFVRYWTEDSTATEIIPVVRIFQKMYNEQ-GTVMKDNVGI 129

  Fly   121 LTEILKNPPGYYDVILLEQFNTDC--------------AMSVAHVFQAPVIGMSSCALMPWHYER 171
            |.|:.|..   :|||:.|.:....              ::||||        .:|.|:      .
Worm   130 LNELKKRK---FDVIIFEAYIYSAYPLMDYLEIPTFIPSVSVAH--------DTSLAI------E 177

  Fly   172 FGAPLIPSYISALFQGQSQEMSFAGRLGNWITVHSLNLL-----YKMFTVPAGNALIRQRFGPGL 231
            .|.|::||.:|........::|...|..|...|...:.:     ::.|..|.....||
Worm   178 IGEPVMPSVVSDCLSPFGDKLSITERAFNAFMVPYFDFMIGYPTHRSFKPPYNPIDIR------- 235

  Fly   232 PSTEDLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISP----PKPLPSDLQKILDNAPKGVI 292
                .:|...|.:.:|.:..:..|:|.....|::||:.:..    .:.|.....:||....| .:
Worm   236 ----SIVPEASFVFLNSNPFVDFPRPTLTKTIQIGGISVDSNELRSQKLDETWSEILKLREK-TM 295

  Fly   293 LISWGSQLKACSLSAARRDGIVKAIGRLEQ-EVIWKYENDT---LPNKPPNLHIRKWLPQRDILA 353
            |:|:||.|.:..:....:..:..|:.:.:. ..|||||:|:   ......|:|..||:||..:||
Worm   296 LVSFGSMLYSKDMPFKNKIALKNAMEKFKNVTFIWKYEDDSSDEFAKGIENIHFAKWVPQTALLA 360

  Fly   354 HPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKL-DENTVYEA 417
            ...|..|::|.||....|......|.:..|...||..|...||:...:::|....| |...:..|
Worm   361 DSRLSAFLTHAGLGSINELSYLGKPAILCPQLFDQMRNAKMLVRHNGSIELSKYDLGDSEKIVNA 425

  Fly   418 LTKAL-DPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDV 481
            ....| |.|:...|.::|....|:...|.|..:...|..|.....|...|.:..::...|:.:|
Worm   426 FQAILFDSSYAKNALKLAEQLENQPIKPKEMMVKHAEFAARFGRLPSLDPYSRKMTFIEYFLID- 489

  Fly   482 YSVVALSLLLPVITLLGLIRMFK 504
              |.|:|:::.:..:..:.:|||
Worm   490 --VAAISMVVLIAVVFVITKMFK 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	119/497 (24%)
ugt-39	NP_504816.2	Glycosyltransferase_GTB_type	12..503	CDD:299143	124/526 (24%)
ugt-39	NP_504816.2	UDPGT	29..521	CDD:278624	122/515 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161422
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740