Protein Alignment Ugt36E1 and Ugt2b10

DIOPT Version :10

• Sequence 1: NP_609911.1
• Gene: Ugt36E1 / 35139
• FlyBaseID: FBgn0027070
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001178605.1
• Gene: Ugt2b10 / 305264
• RGDID: 1309989
• Length: 532
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 152/554 - (27%)
• Similarity: 263/554 - (47%)
• Gaps: 77/554 - (13%)

  Fly    10 LLALLSLVAFSDS---LRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISP-----FEDKDPP 66
            ||.||.|..|..|   .::| ::| ...||:.....|:..|.:.||.|.|:.|     :|..:
  Rat    10 LLLLLQLSDFFGSGTGGKVL-VWP-MEFSHWLNLRVILDELLKKGHEVTVLRPSASLSYEVDN-- 70

  Fly    67 NGYKDHLLPPSTLTDTISLEDFERPYSFLFHYVEFF------ILHKMGRED-------------- 111
                         |..|..|.:...|| |....|||      .::::.::.
  Rat    71 -------------TSAIEFETYPTSYS-LTEVDEFFWESLRKYIYELPKQSFWGYFLMFQELVWV 121

  Fly   112 --------CNTTLHSRALTEILKNPPGYYDVILLEQFNTDCAMSVAHVFQAPVIGMSSCALMPWH 168
                    |...:.::.|...|:|  ..:||||.:.| ..|...:|.:.:.|::  .|....|..
  Rat   122 DSDYFESLCKDVVFNKELMTKLQN--SGFDVILADPF-IPCGDLLAEILKIPLV--YSLRFFPGS 181

  Fly   169 -YERF--GAPLIPSYISALFQGQSQEMSFAGRLGNWITVHSLNLLYKMFTVPAGNALIRQRFGPG 230
             ||::  |.|:.|||:.......|..|:|..|:.:.|.|...:..::.|.....|.|..:..  |
  Rat   182 TYEKYSGGLPMPPSYVPIAMSELSDRMTFVERMKHMIYVLCFDFWFQAFNEKKWNELYTEVL--G 244

  Fly   231 LPST-EDLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILDNAPK-GVIL 293
            .|:| .:.:....:.|:..::.|..|.|:.||...|||:|..|.||||.:::..:.::.: ||::
  Rat   245 RPTTLSETMAKADIWLIRTYWDLEFPHPVLPNFDFVGGLHCRPAKPLPKEIEDFVQSSGEHGVVV 309

  Fly   294 ISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWKYENDTLPNKPPNLHIRKWLPQRDILAHPNLK 358
            .|.||.:.  :|:..|.:.|...:.::.|:|:|::|.........|..:.||:||.|:|.||..:
  Rat   310 FSLGSMVG--NLTEERANVIAAGLAQIPQKVLWRFEGKKPETLGSNTRLYKWIPQNDLLGHPKTR 372

  Fly   359 VFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEAL-TKAL 422
            .|::|||..|..||:...:|:||:|::|||..||..|..:|.|::|:...:....::.|| |...
  Rat   373 AFITHGGTNGIYEAIYHGIPVVGIPLFGDQYDNIVHLKTKGAAVRLDFLTMSSTDLFTALKTITN 437

  Fly   423 DPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSVVAL 487
            |||:|..|..::..::::...||:.|::|:|.|...|||...:.:|..||...|:||||...
  Rat   438 DPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWVQYHSLDVIGF--- 499

  Fly   488 SLLLPVITLLGLIR---MF-KRREPKGDRKLKRK 517
             ||..|:|::.:::   :| .::..|..||.||:
  Rat   500 -LLACVVTVMFILKKCCLFCCQKFTKAGRKKKRE 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	GT1_Gtf-like	23..453	CDD:340817	122/468 (26%)
Ugt2b10	NP_001178605.1	UDPGT	26..529	CDD:278624	142/533 (27%)