DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36E1 and Ugt3a2

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	XP_038959826.1	Gene:	Ugt3a2 / 294793	RGDID:	1564365	Length:	454	Species:	Rattus norvegicus

Alignment Length:	481	Identity:	124/481 - (25%)
Similarity:	220/481 - (45%)	Gaps:	75/481 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 DTISLEDFERPYSFLFHY-------------VEF-----FILHKMGREDCNTTLHSRALTEILKN 127
            :|.|:|. ..|.:.:.||             ::|     ..:|:...:.||..|..:.:.|.|||
  Rat     3 ETFSIEK-SHPGNRIMHYRVDLCPQKVKLNKLQFEHHTIVKIHRHFGDLCNHLLSRKDIMEFLKN 66

  Fly   128 PPGYYDVILLEQFNTDCAMSVAHVFQAPVIGMS-SCALMPWHYERFGAPLIPSYISALFQGQSQE 191
              ..:|::|.|..:...::.|..:.:..|:.:: ....|.:..:|  .||  ||:.....|.:.:
  Rat    67 --ANFDLVLFESVDYCSSLIVEKLGKQFVLFLAFQLGFMDFELQR--VPL--SYVPVYGSGLTDQ 125

  Fly   192 MSFAGRLGNWITVHSLNLLYKMFTVPAGNALIRQRFGPG-LPSTEDLVRNTSLMLVNQHFSLSGP 255
            |.|.||:.|::....|:...:.. :...::.|::.|..| .|...||:....|..||..|:....
  Rat   126 MDFWGRVKNFLMFFDLSRKQREI-LSQYDSTIQEHFAEGSRPVLSDLLLKAELWFVNCDFAFEFA 189

  Fly   256 KPLPPNVIEVGGVHISPPKPLPSDLQKILDN-APKGVILISWGS-----QLKACSLSAARRDGIV 314
            :||.||::.|||:...|.:.:|.||:..:.. ...|.:|::.|:     |.|.          |:
  Rat   190 RPLFPNIVYVGGLLDKPVQSIPQDLENFITQFGDSGFVLVALGTVATKFQTKE----------II 244

  Fly   315 K----AIGRLEQEVIWKYENDTLPNK---PPNLHIRKWLPQRDILAHPNLKVFMSHGGLMGTTEA 372
            |    |...|.|.|||..::...|..   .||:.|..||||.|:||||::::|::|||:....||
  Rat   245 KEMNNAFAHLPQGVIWACKDSHWPKDVTLAPNVKIMDWLPQTDLLAHPSIRLFVTHGGMNSVNEA 309

  Fly   373 VSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKAL-DPSFKARA---KEV 433
            :...||:||:..:.||..|:..:..:.:.:.::::.|...|....:.:.: |..:|:.|   |.:
  Rat   310 IQHGVPMVGILFFSDQPENMIRVEAKTIGVSIQIQTLKAETFARTMKEVIEDKRYKSAAMASKII 374

  Fly   434 ASSY----NNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSVVALSLLLPVI 494
            ..|:    :.|::|       |::|:.:|.||...:|.|........|.|||: :..|.|.|..:
  Rat   375 RHSHPLTPSQRLEG-------WIDHILQTGGAAHLKPYAFQQPWHEQYLLDVF-LFLLGLTLGTV 431

  Fly   495 TL----LGLIRMFKRREPKGDRKLKR 516
            .|    ||.:    .|...|.||.|:
  Rat   432 WLCVKVLGAV----MRYLSGARKAKQ 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	105/419 (25%)
Ugt3a2	XP_038959826.1	Glycosyltransferase_GTB-type	49..419	CDD:415824	103/393 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344003
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740