DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and Ugt2b

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_113721.5	Gene:	Ugt2b / 24862	RGDID:	3936	Length:	530	Species:	Rattus norvegicus

Alignment Length:	517	Identity:	138/517 - (26%)
Similarity:	246/517 - (47%)	Gaps:	66/517 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SHFKFFHPIMRGLAEAGHSVDVISP----FEDKDPPNGYKDHLLPPSTLTDT-----ISLED--- 87
            ||:.....|:..|.:.||.|.|:.|    |.|....:..|..:...|...|.     |.|.|
  Rat    34 SHWMNIKIILDELVQRGHEVTVLKPSAYFFLDPKKSSDLKFEIFSTSISKDELQNHFIKLLDVWT 98

  Fly    88 FERP---------------YSFLFHYVEFFILHKMGREDCNTTLHSRALTEILKNPPGYYDVILL 137
            :|.|               |.|.:.|:..          |...:.::.|  :.|.....:||:..
  Rat    99 YELPRDTCLSYSPILQNLVYEFSYFYLSI----------CKDAVSNKQL--MTKLQESKFDVLFA 151

  Fly   138 EQFNTDCAMSVAHVFQAPVIGMSSCALMPWH-----YERFGAPLIPSYISALFQGQSQEMSFAGR 197
            :.. ..|...:|.:...|.  :.|.:..|.|     ..:|..|  |||:..:..|.:.:|:|..|
  Rat   152 DPV-ASCGDLIAELLHIPF--LYSLSFSPGHKLEKSIGKFILP--PSYVPVILSGLAGKMTFIDR 211

  Fly   198 LGNWITVHSLNLLYKMFTVPAGNALIRQRFGPGLPST-EDLVRNTSLMLVNQHFSLSGPKPLPPN 261
            :.|.|.:...:..:::......:....:..  |.|:| ::.:....:.|:..::.|..|.|..||
  Rat   212 VKNMICMLYFDFWFEILRHKEWDTFYSEIL--GRPTTVDETMSKVEIWLIRSYWDLKFPHPTLPN 274

  Fly   262 VIEVGGVHISPPKPLPSDLQKILDNAPK-GVILISWGSQLKACSLSAARRDGIVKAIGRLEQEVI 325
            |..:||:|..|.||||.|:::.:.::.: ||::.|.||.:.  :::..:.:.|..|:.::.|:|:
  Rat   275 VDYIGGLHCKPAKPLPKDMEEFVQSSGEHGVVVFSLGSMVS--NMTEEKANAIAWALAQIPQKVL 337

  Fly   326 WKYENDTLPNKPPNLHIRKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSL 390
            ||::..|.....||..:.|||||.|||.||..|.|::|||..|..||:...:|::|:|::|||..
  Rat   338 WKFDGKTPATLGPNTRVYKWLPQNDILGHPKTKAFVTHGGANGLYEAIYHGIPMIGIPLFGDQPD 402

  Fly   391 NIAALVQRGMALQLELKKLDENTVYEALTKALD-PSFKARAKEVASSYNNRIQGPLETAIWWVEH 454
            |||.:|.:|.|:.|.::.:.:.....||.:.:| |.:|.....:::.::::...||:.|::|:|.
  Rat   403 NIAHMVAKGAAVSLNIRTMSKLDFLSALEEVIDNPFYKKNVMLLSTIHHDQPMKPLDRAVFWIEF 467

  Fly   455 VAETKGAPLTQPSAVHLSRFVYYSLDV-------YSVVALSLLLPVITLLGLIRMFKRREPK 509
            :...|||...:|...:|..:.|:||||       ::|:|   .|.|..||.:.|.|.::|.|
  Rat   468 IMRHKGAKHLRPLGHNLPWYQYHSLDVIGFLLTCFAVIA---ALTVKCLLFMYRFFVKKEKK 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	118/459 (26%)
Ugt2b	NP_113721.5	UDPGT	24..527	CDD:278624	138/517 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810