DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt-10

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_504313.2	Gene:	ugt-10 / 188619	WormBaseID:	WBGene00020594	Length:	536	Species:	Caenorhabditis elegans

Alignment Length:	577	Identity:	148/577 - (25%)
Similarity:	226/577 - (39%)	Gaps:	138/577 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FCLLALLSLVAFSDSL--RILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPF---------- 60
            |....||.|..|...|  .||...|....||.||...:...:|:.||:|.|..||
Worm     3 FSSFFLLILCVFPIILGKNILIFNPIFGFSHVKFVSKLADIIADHGHNVTVFQPFHIALKNTEGL 67

  Fly    61 -EDKDPP--NGYKDH---LLPPSTLTDTISLEDFERPYSFLFHYVEFFILHKMGREDCNTTLHSR 119
             ::|:..  |.|.||   ||...|.|                 :..|:..|.|.....:..:.::
Worm    68 IKNKNIKFINYYPDHYDELLKTETQT-----------------FPMFWDSHLMNNPVVSAVMMAK 115

  Fly   120 AL--------TEILKN-------PPGYYDVILLEQFNTDCAMSVAHVFQAPVIGMSSCALMPWHY 169
            ||        |:::|:       ....:||::.|.|.. ..|.|||:...|.|.:.|........
Worm   116 ALSSTFERTATQLVKDQNVLNNLKSKKFDVMISETFEL-TGMYVAHLINVPCIPIWSAVRFLVFN 179

  Fly   170 ERFGAPLIPSYISALFQGQSQEMSFAGRLGNWITVHSLNLLYKMFTVPAG--------NALIRQR 226
            :.||.|....||.......:.:..|..|         ||.:|:.|....|        |.:|.:.
Worm   180 KAFGQPSTLGYIPLEGSKMAPDFGFFDR---------LNDVYRDFFGQIGMDRLGQYQNNIIEKA 235

  Fly   227 FGPGLPSTEDLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPK-----PLPSDLQKILDN 286
            .|..:|..:|||..:.:.:.|.:..|.......|.::.:||:.|...|     .||.:.:|||..
Worm   236 VGHSVPYWKDLVSQSPIYITNSNPYLDFAVATTPAIVHIGGITIDLEKIKHADELPEEYEKILQE 300

  Fly   287 APKGVILISWGSQLKACSLSAARRDGIVKAIGRL-EQEVIWKYENDTL---PNKPPNLHIRKWLP 347
            . :..:|||:||.:::..:....:.|::|....| :...|||||.|.:   ...|.|:|::||:|
Worm   301 R-ESTVLISFGSVIRSYEMPDNFKAGLIKMFESLPDVTFIWKYERDDVEFQKRLPKNVHLKKWVP 364

  Fly   348 QRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLD-- 410
            |..:||...:|:|::||||..|.|...:..|.:.|||:|||..|...|.:.|.|:..:  |.|
Worm   365 QPSLLADKRVKLFVTHGGLGSTMEVAYTGKPALSVPIFGDQPENADMLARHGGAIAYD--KFDLA 427

  Fly   411 -----ENTVYEALTKALDPSFKARAK---------------------EVASSY-NNRIQGPLETA 448
                 ..||.|.:|   :|.|...|:                     |.|..: |:|.|.|....
Worm   428 NGEKLTKTVREMVT---NPKFSKNAEALRDVLLKQPIDPKMNLMKHLEFAMEFPNHRSQVPAINK 489

  Fly   449 IWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSVVALSLLLPVITLLGLIRMFKR 505
            :.|:.|                      |.|||.:.    |.|.|:..|.||..|.:
Worm   490 LGWIAH----------------------YYLDVIAF----LTLVVVGFLYLIFRFTK 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	137/530 (26%)
ugt-10	NP_504313.2	egt	1..463	CDD:223071	129/492 (26%)
ugt-10	NP_504313.2	UDPGT	31..535	CDD:278624	139/549 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161480
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740