DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36E1 and ugt-30

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_506729.1	Gene:	ugt-30 / 187955	WormBaseID:	WBGene00011340	Length:	535	Species:	Caenorhabditis elegans

Alignment Length:	552	Identity:	138/552 - (25%)
Similarity:	238/552 - (43%)	Gaps:	74/552 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISP---FEDKDPPNGY 69
            ||||      .:|:.|.||...|..|.||.||...:...|.|.||:|..:.|   ...:|...|.
Worm    10 FCLL------LYSNCLNILVYAPAFAASHSKFLGKLADTLTERGHNVTYLMPVVNIAKRDECKGV 68

  Fly    70 K-----------DHLL-------PPSTLTD---TISLEDFERPYSFLFHYVEFFILHKMGREDCN 113
            |           :.:|       |...:.|   |:.::.......|.|...:..|.       |.
Worm    69 KITKDVVIVEAGEKMLSQKQADTPNDEILDVWWTVQMDSSNSREIFQFFCSDMKIA-------CE 126

  Fly   114 TTLHSRALTEILKNPPGYYDVILLEQFNTDCAMSVAHV--FQAPVIGMSSC---ALMPWHYERFG 173
            ..|..|.:.|.:|  ...:|:.:||..:. |.:.....  .:..::..||.   .::|:    .|
Worm   127 NFLSRRDIFEDMK--ARNFDLAILEPVSA-CGLGFVKALGIEKTILASSSVFYDVILPY----IG 184

  Fly   174 APLIPSYISALFQGQSQEMSFAGRLGNWITVHSLNL-LYKMFTVPAGNALIRQRFGPGLPSTEDL 237
            .||..||:.:.:....||:|...:..||:....::: |..:|  .....:.|:..|..|.:...|
Worm   185 EPLDYSYVPSGYSVTGQELSLGEKFENWMVSREISIALEGLF--DGEMEIYRRLLGHNLTNWRHL 247

  Fly   238 VRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHIS----PPKPLPSDLQKILDNAPKGVILISWGS 298
            ..:.|:..||.:.....|:|:....:.:||:.::    ....|..:.:|:|:..|. .:|:|:|:
Worm   248 FPSASIFFVNSNPFFDFPRPVLEKTVPIGGISVNMGVRKEDMLTEEWEKVLNQRPH-TMLVSFGT 311

  Fly   299 QLKACSLSAARRDGIVKAIGRLEQ-EVIWKYEND--TLPNKPPNLHIRKWLPQRDILAHPNLKVF 360
            .:.:..:....|.|:::|...... ..|||||:|  :..|...|::..||:||.::|....|..|
Worm   312 LVMSTHMPKKWRSGLLEAFKSFPNVTFIWKYESDDHSFANGIDNIYFSKWVPQNELLNDNRLTAF 376

  Fly   361 MSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKA---- 421
            :|||||....|...|..|.:.:|::.||:.|...|.:...|:.|...:: :||  |.|.||
Worm   377 LSHGGLGSIMELAFSGKPALIIPVFADQTRNANTLARHRGAICLHKSQM-KNT--EVLKKAFKSV 438

  Fly   422 -LDPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYS-- 483
             .|.|||..:.::|::..|:...|.:|.|.:.|.|.|....|...|...||:.|....:|:|:
Worm   439 LFDASFKNNSLKLAATLRNQPNKPKDTLIKYTEFVGEFGPFPQMDPYGRHLNVFQKSFIDIYTLI 503

  Fly   484 VVALSLLLPVI--TLLGLIRMF--KRREPKGD 511
            :|..|:.:.:|  .:..||:.|  .:...|.|
Worm   504 IVVSSIFVALIFNVIAKLIQYFIKSKSSEKND 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	123/493 (25%)
ugt-30	NP_506729.1	UDPGT	21..529	CDD:278624	130/527 (25%)
ugt-30	NP_506729.1	Glycosyltransferase_GTB_type	<255..524	CDD:299143	76/272 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161391
Domainoid	1	1.000	172	1.000	Domainoid score	I2232
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.790