DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt-38

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_504812.1	Gene:	ugt-38 / 184294	WormBaseID:	WBGene00017333	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	549	Identity:	135/549 - (24%)
Similarity:	214/549 - (38%)	Gaps:	82/549 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLALL-SLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISP-----FEDKDPPNG 68
            ||||| :|.|...|...|...|..|.||.|||..|...|.:|||:|...:|     :.:.:....
Worm     3 LLALLFTLYANVSSFNFLVFCPLFAHSHSKFFATIADSLTDAGHNVAFFTPIIVEKYRNFNYTKS 67

  Fly    69 YKD--HLLPPSTLTD---TISLEDFERPYSFLFHYVEFF----ILHKMGREDCNTTLHSRALTEI 124
            .||  ::.|...|.:   .:|..||.|.::......|..    |..||..|.......:..:...
Worm    68 TKDVVYMEPSKKLKEYGRQMSTGDFVRYWTEDSTATEIITVVRIFQKMYNEQGTVMKDNIEILND 132

  Fly   125 LKNPPGYYDVILLEQFNTDC--------------AMSVAHVFQAPVIGMSSCALMPWHYERFGAP 175
            ||...  :|||:.|.|....              ::||||.....|              ..|.|
Worm   133 LKKRK--FDVIIFEAFIFSAYPLMDYLEIPTFIPSLSVAHDTALAV--------------EIGEP 181

  Fly   176 LIPSYISALFQGQSQEMSFAGRLGNWITVHSLNLL-----YKMFTVPAGNALIRQRFGPGLPSTE 235
            ::||.:|........::|...|..|...|...:.:     ::.|..|.....||
Worm   182 VMPSVVSDCLSPFGDKLSITERAFNAFMVPYFDFMIGYPTHRSFKPPYNPIDIR----------- 235

  Fly   236 DLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISP----PKPLPSDLQKILDNAPKGVILISW 296
            .:|...|.:.:|.:..:..|:|.....|::||:.:..    .:.|.....:||....| .:|:|:
Worm   236 SIVPEASFVFLNSNPFVDFPRPTLTKTIQIGGISVDSNELRSQKLDETWSEILKLREK-TMLVSF 299

  Fly   297 GSQLKACSLSAARRDGIVKAIGRLEQ-EVIWKYENDT---LPNKPPNLHIRKWLPQRDILAHPNL 357
            ||.|.:..:....:..:..|:.:.:. ..|||||:|:   ......|:|..||:||..:||...|
Worm   300 GSMLYSKDMPFKNKIALKNAMEKFKNVTFIWKYEDDSSDEFAKGIENIHFAKWVPQTALLADSRL 364

  Fly   358 KVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLD---ENTVYEALT 419
            ..|::|.||...||......|.:..|...||..|...||:...:  :||.|.|   ...:.||..
Worm   365 SAFLTHAGLGSITELSYLGKPAILCPQLFDQMRNTKMLVRHNGS--IELSKYDLGKSEKIIEAFQ 427

  Fly   420 KAL-DPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYS 483
            ..| |.|:...|:::|....|:...|.|..:...|:.|.....|...|.:..:|...|:.|||.:
Worm   428 AILFDSSYAKNAQKLAEQLENQPIKPKEMMVKHAEYAARFGRLPSLDPYSRKMSFVEYFLLDVAA 492

  Fly   484 VVALSLLLPVITLLGLIR------MFKRR 506
            :....|...|..:..|::      :.||:
Worm   493 ICVFILTFVVFVVTKLVQSLFDIFLIKRK 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	123/495 (25%)
ugt-38	NP_504812.1	Glycosyltransferase_GTB_type	12..512	CDD:299143	127/529 (24%)
ugt-38	NP_504812.1	UDPGT	29..521	CDD:278624	123/521 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161423
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740