DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt-15

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_506211.1	Gene:	ugt-15 / 183462	WormBaseID:	WBGene00008097	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	535	Identity:	131/535 - (24%)
Similarity:	223/535 - (41%)	Gaps:	62/535 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISP--FEDKDPPNGYK--- 70
            |.||.||.   |.::|...|....||..|...|...|.:|||.|.::.|  .|.|....|.|
Worm     9 LLLLELVC---SYKVLVFNPAFGASHSNFLGKISDILIDAGHDVTMLIPVCMESKKDLVGSKKVK 70

  Fly    71 ----------DHLLPPSTLTDTI---SLEDFERPYSFLFHYVEFFILHKMGREDCNTTLHSRALT 122
                      ..|:.....|:.:   .:...:...:..|..::.|.:  .....|.......|:.
Worm    71 KIIRIDQEPRSKLMQEEAKTEEMIKKQIWKLDADITIFFSMIKNFSI--ASGYQCENIFKQTAIL 133

  Fly   123 EILKNPPGYYDVILLEQFNTDCAMSVA-HVFQAPVIGMSSCALMPWHYERFGAPLIPSYISALFQ 186
            |.|:|.  ::|:.:.|.... |...:. .:....:|...|...:.......|.|...||...::.
Worm   134 EQLRNE--HFDLGITESLFI-CGFPLLDSIGVKTIINADSVLYLDVVKHALGEPASTSYYPGVYA 195

  Fly   187 GQSQEMSFAGRLGN-------WITVHSLNLLYKMFTVPAGN-ALIRQRFGPGLPSTEDLVRNTSL 243
            .....|||..|:.|       |         |..:|...|. ..|:..:...| :.||.:...:.
Worm   196 KNIDRMSFRERVRNLFGMAFSW---------YFSWTRFQGELEAIKPYYNKSL-TWEDHINGAAY 250

  Fly   244 MLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILD---NAPKGVILISWGSQLKACSL 305
            ..:|.:..|..|.|..|..:.:||:.::..|.....|:|..|   |..|..:|:|:||...:|.:
Worm   251 YFINSNQYLDYPSPTLPKTVFIGGMQVNTNKHGKVKLEKEWDDLLNLRKQNVLVSFGSNAFSCDM 315

  Fly   306 SAARRDGIVKAIGRL-EQEVIWKY--ENDTLPNKPPNLHIRKWLPQRDILAHPNLKVFMSHGGLM 367
            ....::..:|....: |...||||  ||.||.::..|:.:..|:||.||||...|.:|::||||.
Worm   316 PDEFKESFLKVFASMPETTFIWKYEQENATLADQLSNVKLTTWMPQNDILADERLTLFVTHGGLG 380

  Fly   368 GTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDEN-TVYEALTKALD-PSFKARA 430
            .:.|......|.|.:|:..||..|...|.:.|.||||:...|:.: .:.||:...:: ||:|..|
Worm   381 SSMELAYQGKPAVVIPLMADQPRNALMLTRHGGALQLDKTFLNNSEKIREAIQTVMENPSYKKNA 445

  Fly   431 KEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSVVALSLLLPVIT 495
            :::|:..:::...|.:..:...:...:............||:.|.|||:|    :||:..|.::|
Worm   446 EKLANILSSQPHQPKDVVLKHCDFAVKHGDLKTLNSEGRHLNVFQYYSID----IALAAGLFLVT 506

  Fly   496 LLG-----LIRMFKR 505
            ::.     :|.:||:
Worm   507 IISFIIFTIIFVFKK 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	117/483 (24%)
ugt-15	NP_506211.1	UDPGT	19..506	CDD:278624	121/505 (24%)
ugt-15	NP_506211.1	Glycosyltransferase_GTB_type	<252..493	CDD:299143	68/240 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161437
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.790