DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36E1 and ugt-27

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_491436.1	Gene:	ugt-27 / 182508	WormBaseID:	WBGene00015694	Length:	526	Species:	Caenorhabditis elegans

Alignment Length:	532	Identity:	146/532 - (27%)
Similarity:	228/532 - (42%)	Gaps:	49/532 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNGYKDH 72
            |..|..| |:...:|:.:|...|..|.||..|...:...|.||||:|..:.|..|.........|
Worm     5 FYFLRFL-LIFQVNSINVLVYSPAFAASHTNFMARLADTLTEAGHNVTFLVPIVDVARTKQLGVH 68

  Fly    73 LLPPSTLTDTISLEDFER------PY--SFLFHYVE-------------FFILHKMGREDCNTTL 116
            :     .||.|.:|..|.      |:  |...::.|             ||...|:|   |...|
Worm    69 V-----TTDVIIVEKDEHTTQESVPFDDSMEAYWTEETHSSNVGESFQWFFDGMKLG---CENLL 125

  Fly   117 HSRALTEILKNPPGYYDVILLEQFNTDCAMSVAHVFQ-APVIGMSSCALMPWHYERFGAPLIPSY 180
            ....:.:.||:  ..:||.::|..:. |.:.:|...: ...|..||||...:.:...|.|.:.||
Worm   126 RRHEILDQLKS--RNFDVAIVEPLSV-CGLGLAKKLEIGKTILASSCAYYDYLFRHIGEPDVHSY 187

  Fly   181 ISALFQGQSQEMSFAGRLGNWITVHSL-NLLYKMFTVPAGNALIRQRFGPGLPSTEDLVRNTSLM 244
            :.:|.......|:...||.|.....:: ..:||||  .:..|:.|:.||..:|...||:...||.
Worm   188 LPSLMSTTGDVMTTFERLENHRVAEAMATAMYKMF--DSEKAIYRKHFGDEIPDWRDLLPAASLY 250

  Fly   245 LVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQK----ILDNAPKGVILISWGSQLKACSL 305
            ..|.:..|..|:|:....:.:||:.:...|....:|.|    || |.....:|||:||.:.:..:
Worm   251 FTNSNPYLDFPRPILQKTVSIGGISVDTKKIKSQELDKEWNHIL-NKRNLNMLISFGSMIHSSHM 314

  Fly   306 SAARRDGIVKAIGRLEQEV--IWKYE-NDT-LPNKPPNLHIRKWLPQRDILAHPNLKVFMSHGGL 366
            ....:..::|.| :.|..|  ||||| ||| ......|::..||:||..:|....|..|::||||
Worm   315 LDDAKKNLIKVI-KSEPNVTFIWKYETNDTSFAFGIDNIYFSKWVPQSKLLNDARLTAFLTHGGL 378

  Fly   367 MGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKAL--DPSFKAR 429
            ..|.|......|.|.|||:|||..|...|.:.|.|:.::..:|....:..:..|::  |.::|..
Worm   379 GSTNELAHFGKPAVMVPIFGDQYRNGHMLQRHGCAIIVQKTELSNWKIVSSAVKSVLYDENYKKN 443

  Fly   430 AKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSVVALSLLLPVI 494
            |..:|....|:...|.|..:.:||.||.....|........|:......||||.:......|..:
Worm   444 AAHLADLLQNQPVKPKEIVVKYVEFVARFGPFPEMDAYGRQLNFIQRNLLDVYLIELFGHFLFFL 508

  Fly   495 TLLGLIRMFKRR 506
            .:..||.:..:|
Worm   509 IIFCLIPLQLKR 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	136/484 (28%)
ugt-27	NP_491436.1	UDPGT	21..500	CDD:278624	137/493 (28%)
ugt-27	NP_491436.1	egt	<230..478	CDD:223071	77/249 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161459
Domainoid	1	1.000	172	1.000	Domainoid score	I2232
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.790