DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt-50

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_741913.1	Gene:	ugt-50 / 181413	WormBaseID:	WBGene00011564	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	560	Identity:	123/560 - (21%)
Similarity:	226/560 - (40%)	Gaps:	105/560 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WKVFCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDK--DPPN 67
            |..|||.|||......::.:||...|..:.||..........|..|||...:..|...|  |..:
Worm     8 WMFFCLTALLHGSFIVNAAKILVYCPSISKSHVLLCSKYADLLHNAGHDTVLFIPSYSKLLDNYD 72

  Fly    68 GYKDHLLPPSTLTDTISLEDFERPYSFLFHYVEFFILHKMGREDCNTTLHSRALTEILKNPP-GY 131
            |.|                           :.:.:.||.: .|..:|.|.:  |..:::|.. |:
Worm    73 GAK---------------------------HAKVWRLHNV-TEAYDTKLGT--LANVMENSHIGF 107

  Fly   132 --------------------------------YDVILLEQFNTDCAMSVAHVFQAP-VIGMSSCA 163
                                            :|:::..:.: .|..::..:|..| .:.:||.|
Worm   108 IDRLTFDADFWIDMCADLLGKLPEMQHIIDYKFDLVIYNEID-PCTPAIVRLFNIPKTVLLSSEA 171

  Fly   164 LM---PWHYERFGAPLIPSYISALFQGQSQE-MSFAGRLGN------WITVHSLNLLYKMFTVPA 218
            :|   .|:   .|.|.:|||:.::.:..:.: |||..|:.|      .|.||.|..::.:
Worm   172 IMDKVAWN---LGLPTLPSYVPSVEENPNHDRMSFFERMSNVYKFFQSIVVHYLQDIHVL----- 228

  Fly   219 GNALIRQRFGPGLPSTEDLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPK--PLPSDLQ 281
              .|.|:......||..:::||.||:|||.......|:......:.||.:.....:  .||....
Worm   229 --NLFRKEVSSDFPSIAEIIRNVSLVLVNTDEIFDLPRSYSSKFVYVGMLEAGKDENVTLPKKQD 291

  Fly   282 KILDNAPKGVILISWGSQLKACSLSAARRDGIVKAIGRL-EQEVIWKYENDTLPNKP-----PNL 340
            ........|.:.:|:|:.....||....:..|:.||.:| :...:.|...|...:..     .|:
Worm   292 DYFKKGKSGSVFVSFGTVTPFRSLPERIQLSILNAIQKLPDYHFVVKTTADDESSAQFFSTVQNV 356

  Fly   341 HIRKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLE 405
            .:..|:||:.:|.|.|||:|:||||:....|.:...||:|.:|::.||..|...:.:||....:.
Worm   357 DLVDWVPQKAVLRHANLKLFVSHGGMNSVLETMYYGVPMVIMPVFTDQFRNGRNVERRGAGKMVL 421

  Fly   406 LKKLDENTVYEALTKAL-DPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAV 469
            .:.:.:.|.::|:...| :.|:.:..|.::....|:.....|....|::.|.:.:.:......:.
Worm   422 RETVVKETFFDAIHSVLEEKSYSSSVKRISHLMKNKPFTSEERVTKWIDFVLKYETSEHFDLESN 486

  Fly   470 HLSRFVYYSLDVYSVVALSLLLPVITLLGLI---RMFKRR 506
            :||...:..||::      ..|.:|:||..:   ::|||:
Worm   487 NLSIIEHNHLDLF------FYLCIISLLNFVVYRKIFKRK 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	112/509 (22%)
ugt-50	NP_741913.1	egt	9..475	CDD:223071	111/506 (22%)
ugt-50	NP_741913.1	UDPGT	26..520	CDD:278624	115/540 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810