DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt-4

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001041203.1	Gene:	ugt-4 / 179754	WormBaseID:	WBGene00013905	Length:	535	Species:	Caenorhabditis elegans

Alignment Length:	561	Identity:	142/561 - (25%)
Similarity:	232/561 - (41%)	Gaps:	88/561 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KVFCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNGYK 70
            :|.|:|....||:..:|.:.|.:.|....||.||...|...||:.||.|....||..:    .|.
Worm     3 RVLCVLLFSVLVSHVESYKFLVISPVYGYSHMKFMAIIANQLADEGHQVTYFQPFVIE----AYL 63

  Fly    71 DHLLPPSTLTDTIS----------------LED------FERPYSFLFHYVEFFILHKMGREDCN 113
            ||.|..::|.|.|:                |.|      ::...|.:|...:|.:  ......|.
Worm    64 DHKLLNNSLIDVINYWHDEEGRRHIPPSNDLHDAWYSSKYQSALSAVFDMPQFLV--SAWEHMCR 126

  Fly   114 TTLHSRALTEILKNPPGYYDVILLEQFNTDCAMSVAHVFQAPVI-----GMSSCALMPWHYERFG 173
            .......|.:|||:..  :||::.|.|:. |.:.:|...|:..|     |....|:.    :..|
Worm   127 KIFQDSELHKILKDKD--FDVVIAETFDF-CGLYLADYIQSKSIVSVFTGSRLIAIT----DPLG 184

  Fly   174 APLIPSYISALFQGQSQEMSFAGRLGNWITVHS-LNLLYKMFTVPAGNALIRQ-RFGPGLPSTED 236
            .|....||.|         ..:...|:..::.. :|.||..:...:|.::|.. ::......|..
Worm   185 EPSSLHYIPA---------PSSDNFGSSASIFDRINDLYHKYVFGSGYSIIFDWQYNQIARLTHG 240

  Fly   237 LVRNTSLML--VNQHFSLSGP-----KPLPPNVIEVGGVHI--SPPKPLPSDLQKILDNAPKGVI 292
            .||:...:|  |..||:.|.|     .|....||.:||..:  |....:|.:...|| |.....:
Worm   241 KVRHWKKILKDVTYHFANSNPYLDFAAPTISKVIPIGGYDMDKSIQTKIPDEFDSIL-NERSLTV 304

  Fly   293 LISWGSQLKACSLSAARRDGIVKAIGRLEQEV--IWKYENDT---LPNK-PPNLHIRKWLPQRDI 351
            .:|:||.:||..:..:.::.:::......|.:  :||||:.|   ..|: |.|:.::.|.|||.:
Worm   305 YVSFGSMVKAKFMPESYKEAMLRMFTANTQNITFLWKYEDPTDIFFKNRLPKNVILKDWFPQRAL 369

  Fly   352 LAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYE 416
            ||...:|:|::||||..|.|...:|.|.:.:|:..:|..|...|.:.|.|   |:....:...:|
Worm   370 LADKRVKLFITHGGLGSTMELAYAAKPAIVIPLIAEQPDNGKMLARHGSA---EIYSKHDIPHWE 431

  Fly   417 ALTKALD-----PSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVY 476
            .|.:.|.     .|::..|..:|...:|:...|.|..|...|..|.....|...||...:|...:
Worm   432 KLNRLLQKMLQHSSYQKAADRLARVLSNQPIKPRELMIKHSEMAAMFGKMPELTPSVQDMSIIEF 496

  Fly   477 YSLDVY----------SVVALSLLLPVITLLGLIRMFKRRE 507
            |:||:.          ||:....|..|:|..|   .||.:|
Worm   497 YNLDIIFLFLIISIGTSVLLWKFLYFVLTDSG---SFKSKE 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	126/502 (25%)
ugt-4	NP_001041203.1	egt	1..473	CDD:223071	124/495 (25%)
ugt-4	NP_001041203.1	UDPGT	21..500	CDD:278624	125/504 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161333
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740