DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt-5

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_506200.1	Gene:	ugt-5 / 179753	WormBaseID:	WBGene00013906	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	557	Identity:	138/557 - (24%)
Similarity:	220/557 - (39%)	Gaps:	77/557 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VFCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISP-----FEDKD-- 64
            :|.||.:.::.:::    .|.:.|....||.|....|...||:|||.|....|     |:|.|
Worm     9 IFVLLFIKNVASYN----FLVISPVYGFSHMKSMAIIANQLADAGHQVTYFQPFVVELFKDHDLI 69

  Fly    65 -PPN----GY------KDHLLPPSTLTDTISLEDFERPYSFLFHYVEFF---ILHKMGREDCNTT 115
             .||    .|      |.::...|.|:|..:...::....     .:.|   |||:..:|.|...
Worm    70 KNPNIEIMNYFHDEEGKKNIPGHSVLSDAWTSYKYQSDVG-----QKIFAPRILHQSFQEMCRHM 129

  Fly   116 LHSRALTEILKNPPGYYDVILLEQFNTDCAMSVAHVFQAPVI-----GMSSCALMPWHYERFGAP 175
            ....||...||:..  :||:|.|.|:. |.:.:|...:.|.|     |....|:.    ...|.|
Worm   130 FEDEALHRQLKDKK--FDVVLSETFDF-CGLYLADYLEMPAIISVFTGNRLNAIT----NALGEP 187

  Fly   176 LIPSYISALFQGQSQEMSFAGRLGN-WITVHSLNLLYKMFTVPAGNALIRQRFGPGLPSTEDLVR 239
            ....|:.:.....:..||...|..| |         :|:.:......|..:::......|....|
Worm   188 SFLHYLPSPSSSFNANMSLYDRFNNFW---------HKILSSSTFGELFDRQYADVYRLTNGKAR 243

  Fly   240 NTSLML--VNQHFSLSGPK-----PLPPNVIEVGG--VHISPPKPLPSDLQKILDNAPKGVILIS 295
            :...:|  |..|||.|.|.     |....||.:||  :......|:..||..|| |.....:.||
Worm   244 HWKQILNDVTYHFSNSNPYLDFVIPTIAKVIPIGGYTMDYKQVPPVSKDLDTIL-NLRSSTVFIS 307

  Fly   296 WGSQLKACSLSAARRDGIVKAI-GRLEQEVIWKYEND----TLPNKPPNLHIRKWLPQRDILAHP 355
            :|:.:.|..:....:..::... .......:||||..    ...|.|.|:|:..|.||:.:||..
Worm   308 YGTMISAKYMPDEYKQSMIDFFKDNKNVTFLWKYEEPEEKFIKENIPDNVHLSTWFPQQSLLADK 372

  Fly   356 NLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTK 420
            .:|:|::||||..|.|...||.|.:..|::.||..|...|.:.|....|....:........|.|
Worm   373 RVKLFITHGGLGSTMELAYSAKPAIVTPLFADQPSNAQMLERHGSVEVLSKHDIPNWKKQSDLLK 437

  Fly   421 AL--DPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLD--V 481
            .:  |..::..|..:|...||:...|.|..:...|:.|.....|...|.|..:....:|::|  :
Worm   438 TMLADKKYQEAATRLADILNNQPISPRELMLKHAENAARFGKIPSLTPFAKDMGFIEFYNIDLII 502

  Fly   482 YSV-VALSLLLPVITLLGLIRMFKRREPKGDRKLKRK 517
            ||| ..|..:...|.:.|:::...:     .||||.:
Worm   503 YSVSFTLFAIYVTIEIFGIVKNCCK-----TRKLKNE 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	123/495 (25%)
ugt-5	NP_506200.1	egt	6..509	CDD:223071	131/525 (25%)
ugt-5	NP_506200.1	UDPGT	32..527	CDD:278624	129/516 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161335
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740