DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt-9

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_504312.1	Gene:	ugt-9 / 178883	WormBaseID:	WBGene00020587	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	561	Identity:	148/561 - (26%)
Similarity:	242/561 - (43%)	Gaps:	86/561 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPF-------------E 61
            ||::|.:::......||...|....||.||...:...:|:.||:|.|..||             :
Worm     6 LLSILLVISLVSCKNILVYNPIFGYSHAKFVSQLANIIADHGHNVTVFQPFHIALKNTDGLIKNK 70

  Fly    62 DKDPPNGYKDH---LLPPSTLTDTISLEDFERPYSFLFHYVEFFILHK-MGREDCNTT---LHSR 119
            :.:..|.|.||   ||...|.|    ..||...:......:..|::.| :|.|...||   ...:
Worm    71 NIEIINYYPDHYAELLKKKTPT----FPDFWDSHLMNNPVLSSFLMPKALGGEFEQTTTQLFQDQ 131

  Fly   120 ALTEILKNPPGYYDVILLEQFNTDCAMSVAHVFQAPVIGMSSCALMPWHYERFGAPLIPSYISAL 184
            .:...|||  ..:||:|.|.|.. ....:|.:.:.|.|.:.|...:|.....||.|.|..|....
Worm   132 KILNDLKN--RNFDVLLAETFEI-AGFYIADLLEIPSIPLMSAVRLPIIDSAFGQPSILGYFPQQ 193

  Fly   185 FQGQSQEMSFAGRLGNWITVHSLNLLYKMF--------TVPAGNALIRQRFGPGLPSTEDLVRNT 241
            :...:.|..|..|         ||.||::|        .....|..|::..|..:|...|||:.:
Worm   194 YSKVAPEAGFLDR---------LNDLYRIFFWNLTTQRLCQFQNDFIQKAIGHPVPHWRDLVKES 249

  Fly   242 SLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPK-----PLPSDLQKILDNAPKGVILISWGSQLK 301
            .:.:.|.:..|....|....::.|||:.|...|     .|..:.:.||... :..:.||:||.::
Worm   250 PIYITNSNSYLDFAVPTTATIVHVGGITIDLEKMRHVAALTEEYENILAER-ESTVFISFGSVIR 313

  Fly   302 ACSLSAARRDGIVKAIGRL-EQEVIWKYENDTL--PNK-PPNLHIRKWLPQRDILAHPNLKVFMS 362
            :..:....:.||:|....| :...|||||.|.:  .|: |.|:|::||:||..:||...:|:|::
Worm   314 SYEMPDNFKAGIIKMFKSLPDVTFIWKYEKDDVKFQNRLPKNVHLKKWVPQPSLLADKRVKLFVT 378

  Fly   363 HGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKAL----- 422
            ||||..|.|...:..|.:.|||:|||..|...|.:.|.|:..:...|.:.   |.|||.:
Worm   379 HGGLGSTMEVAYTGKPALMVPIFGDQPNNADMLARHGGAVAYDKFDLADG---EKLTKTVRDMVT 440

  Fly   423 DPSFKARAKEVASSYNNRIQGP-------LETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLD 480
            :..::..|:|:....:.:...|       ||.|:.:.:|.::.       |:........:|.||
Worm   441 NSKYEVNAQELLKVLSKQPIDPKLNLMKHLEFAMEFPKHRSQV-------PAINRTGLIAHYYLD 498

  Fly   481 VYSVVALSLLLPVITLLGLIRMFK----RREPKGDRKLKRK 517
            |..|:.|:      ::.||..:||    .|:....||:||:
Worm   499 VIGVLTLA------SIFGLFVIFKILNILRKMISLRKVKRE 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	132/498 (27%)
ugt-9	NP_504312.1	egt	20..462	CDD:223071	124/461 (27%)
ugt-9	NP_504312.1	UDPGT	30..532	CDD:278624	140/534 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161481
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740