DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt-53

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_503771.1	Gene:	ugt-53 / 178744	WormBaseID:	WBGene00020182	Length:	515	Species:	Caenorhabditis elegans

Alignment Length:	534	Identity:	142/534 - (26%)
Similarity:	230/534 - (43%)	Gaps:	63/534 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVI----------SPFED-- 62
            |:.|..|:.||..|.||..:.....||..:....:..|...||:|||:          ..|.|
Worm     4 LIFLTVLINFSSCLNILFYYAVIGPSHIAYLRNTIGKLLARGHNVDVVFAVYNELANLDLFPDVR 68

  Fly    63 ------KDPPNGYKDHLLPPSTLTDTISLEDFERPYSFLFHYVEFFILHKMGREDCNTTLHSRAL 121
                  ...|:.:|.:....|.:        ||:..:.|   .||.|.|:.|.:.|...::...|
Worm    69 RIYYNRHADPDYWKKNANHFSNM--------FEKSPTPL---GEFEIFHESGYQLCKIAINDLKL 122

  Fly   122 TEILKNPPGYYDVILLEQFNTD---CAMSVAHVFQAPVIG--MSSCALMPWHYERFGAPLIPS-Y 180
            .|.||:  |.||:    .|::|   |...:......|.||  :::...:| |....|.|.:.| |
Worm   123 IEFLKS--GKYDI----GFSSDYDPCGNILMTAAGIPSIGSLIATPIFLP-HIVSAGLPTVASVY 180

  Fly   181 ISALFQGQSQEMSFAGRLGNWITVHSLNLLYKMFTVPAG-----NALIRQRFGPGLPSTEDLVRN 240
            .::|:  ...:.|...::.|.|     .|.|..:.:...     |.||.:|||...|....:.|.
Worm   181 GTSLY--PEHDSSLYDKIFNLI-----RLTYYHYAISPDMDRKYNNLITKRFGNNFPDVGTIERG 238

  Fly   241 TSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILDNAPKGVILISWGSQLKACSL 305
            ..::.||.|..|...:|:.|.:..:||:.|...|.||.:.:|||.......:|.|:|:|:....:
Worm   239 IDIIFVNSHDFLEQQRPMSPKIKYIGGMAIRKAKQLPDEFEKILSVPKSAYVLFSFGTQVPTAKM 303

  Fly   306 SAARRDGIVKAIGRLEQ-EVIWKYENDTLP----NKPPNLHIRKWLPQRDILAHPNLKVFMSHGG 365
            ....|...|.|..:... ..:|||::..|.    ....|:|..:||||.::|....:|:|:||.|
Worm   304 PLPIRRNFVGAFKKFPNVTFLWKYDSLELDADIFQGVENIHRLEWLPQTELLHDNRVKLFISHMG 368

  Fly   366 LMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKALD-PSFKAR 429
            |....|..::.||::.:|::.||..|......|||.|.|:..||....:..||.:.|: |.:.:.
Worm   369 LNSYLETATAGVPVLSIPLFADQQNNAQNTRDRGMGLLLDRDKLTTKNIESALHELLENPKYLSN 433

  Fly   430 AKEVASSYNNRIQGPLETAIWWVEHVAETK--GAPLTQPSAVHLSRFVYYSLDVYSVVALSLLLP 492
            |:.::.....:.....:|.|.|:|..|...  |..|..|.| .||.|.||..|:..:|...|.:.
Worm   434 ARSISKMILEKPDKANDTFIHWLEFTARNPGLGRVLKLPGA-ELSPFYYYCGDILLLVFCILFII 497

  Fly   493 VITLLGLIRMFKRR 506
            :.|:|..|.:..|:
Worm   498 LHTVLRTINLPSRK 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	126/486 (26%)
ugt-53	NP_503771.1	UDPGT	29..497	CDD:330975	130/493 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14449
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810