DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36E1 and ugt-24

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_500931.3	Gene:	ugt-24 / 177380	WormBaseID:	WBGene00016762	Length:	528	Species:	Caenorhabditis elegans

Alignment Length:	528	Identity:	129/528 - (24%)
Similarity:	224/528 - (42%)	Gaps:	68/528 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDK----------------DPPNGYKDHLLPP 76
            |:.|   ||.|..:.:...|.:|||:|.:..|..:.                :|.....:.:...
Worm    28 LYGH---SHIKVLNTVADTLTDAGHNVTIFRPIIESSQLDKSSVKTKNVIYIEPDEEVVEKMSKI 89

  Fly    77 STLTDTISLEDFERPYSFLFH---YVEFFILHKMGREDCNTTLHSRALTEILKNPPGYYDVILLE 138
            ...:.::...|...|.:.:..   .|.||     |.: |...:..:.:.:.|::.  .:|:.:.|
Worm    90 DQFSGSLWTFDSTHPSAMIAKSNALVGFF-----GTQ-CKKVMRQQKILDQLRDE--NFDLAITE 146

  Fly   139 QFNTDCAMSVAHVFQ-APVIGMSSCALMPWHYERFGAPLIPSYISALFQGQSQEMSFAGRLGNWI 202
            ..: .||.::....: ...:.:.||.......:..|.|:.|||:.......:..|:...||.|:|
Worm   147 PVD-GCAYAIFEYLKIRDHVTVLSCVRFDHVSDILGQPIAPSYVPGTQSFFNDRMTMKERLLNFI 210

  Fly   203 TVH-----SLNLL---YKMFTVPAGNALIRQRFGPGLPSTEDLVRNTSLMLVNQHFSLSGPKPLP 259
            ..:     ..|:|   |:|    |.:.|..||      |..:::...|.:..|....|..|.|..
Worm   211 QFYYGRFTFANILDQEYEM----AKDILGIQR------SWREVLPEASFIFSNHIPVLDFPSPTF 265

  Fly   260 PNVIEVGGVHI-SPPKPLPSDLQ--KILDNAPKGVILISWGSQLKACSLSAARRDGIVKAIGRL- 320
            ..:|.:||..: :..|.|..|.:  .|| |..|..:|||:||..|:..:....:..:::....:
Worm   266 DKIIPIGGFTVKTNEKSLKIDKKWDAIL-NIRKKNVLISFGSNAKSKDMPEEYKKTLLRVFSSMP 329

  Fly   321 EQEVIWKYE--NDTLPNKPPNLHIRKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVP 383
            :...|||||  |..:.....|:.|..||||.::||...:.||::||||....|......|.:.:|
Worm   330 DTTFIWKYEDPNVNIAKNLDNVFISSWLPQNELLADSRVTVFVTHGGLASVMELALMGKPAIMIP 394

  Fly   384 IYGDQSLNIAALVQRGMALQL---ELKKLD--ENTVYEALTKALDPSFKARAKEVASSYNNRIQG 443
            |:.||..|...|.:.|.|..|   :|...|  .:|:.:.|||   ||:|..||::|...||:...
Worm   395 IFADQGRNAQMLKRHGGAAVLQKTDLSNFDLVRDTLNDVLTK---PSYKLNAKKLAEMLNNQPTN 456

  Fly   444 PLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSVVALSLLLPVITL-LGLIR-MFKRR 506
            ..|..:..||..|.....|:......|.:...||.:|:.::: ||:|:.|..: :.|:| |..|.
Worm   457 AKEVLVKHVEFAARFGKLPMLDNYGRHQNIVEYYFIDILTII-LSVLISVFYIFVRLLRFMLSRN 520

  Fly   507 EPKGDRKL 514
            ....|:::
Worm   521 RSTKDKRV 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	115/470 (24%)
ugt-24	NP_500931.3	UDPGT	32..519	CDD:278624	125/510 (25%)
ugt-24	NP_500931.3	egt	<251..504	CDD:223071	77/257 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.860