DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36E1 and ugt-60

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001021158.1	Gene:	ugt-60 / 176366	WormBaseID:	WBGene00007402	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	511	Identity:	132/511 - (25%)
Similarity:	236/511 - (46%)	Gaps:	37/511 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VFCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFE-------DKD 64
            :||:  .||:|   ||||||.:.|....||..|.:.:...|...||.|.:.:..|       :..
Worm     5 IFCI--FLSVV---DSLRILQIVPGFTNSHVLFNYRLAETLRFLGHDVKMWTQMEMAMLDTGNNK 64

  Fly    65 PPNGYKDHLLPPSTLTDTISLEDFERPYSFLFHYVEFFILHKMGREDCNTTLHSRALTEILKNPP 129
            .|.|..::.: |...|||:..|..:...|.:|...:...|...|:|  ...:...|..::|::..
Worm    65 LPEGVSEYRI-PIHFTDTLKTEGLKVFQSMMFESGDAHDLWWTGQE--FKDMRVEACEQMLRHDE 126

  Fly   130 GYYD-------VILLEQFNTDCAMSVAHVFQAP-VIGMS-SCALMPWHYERFGAPLIPSYISALF 185
            ..|:       .:.:..|:..|.:::|...... ||.:: ..::..:...:.|...|||.|....
Worm   127 SVYEDFRKDGFDVAIAHFHDLCPLAIAKKMNVKRVIWITHGTSIYEFSAVQLGLRTIPSTIPHPL 191

  Fly   186 QGQSQEMSFAGRLGNWITVHSLNLLYKMFTVPAG-----NALIRQRFGPGLPSTEDLVRNT-SLM 244
            ........|..|:.|  |:..|:|| ....:|..     |...|:..|.......||.:.| ..:
Worm   192 SSAGFSQLFLDRVQN--TLWHLSLL-DFVNLPQNLLVDENLFYREFVGADQDDLWDLAKTTVPSL 253

  Fly   245 LVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSD--LQKILDNAPKGVILISWGSQLKACSLSA 307
            |:|....|..|:|||.::...|.:.:|..|.|..:  |:.|::....|:|:.|.|:.....::.|
Worm   254 LINGDRMLDFPRPLPIHIAFSGELGVSKGKKLVMEKWLEDIIEKPSDGLIVFSLGTVSNTTNMPA 318

  Fly   308 ARRDGIVKAIGRLE-QEVIWKYENDTL-PNKPPNLHIRKWLPQRDILAHPNLKVFMSHGGLMGTT 370
            ...:..:.|.|:|: ..::|:.|.... ..|..|||:.|||||:||:.||.:|:.::|||.....
Worm   319 QMINSFLGAFGKLKTYTILWRMEKSVAGAEKYENLHLVKWLPQKDIMRHPKMKLMIAHGGYNSFL 383

  Fly   371 EAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKALDPSFKARAKEVAS 435
            ||..:.:|.|.:|::.||.:|.....:.|||..|:...|..|.||.|:.:||.|.:...||::::
Worm   384 EAAQAGIPAVLMPLFADQKINAKRAQRYGMATVLDKLDLTINNVYGAIKEALKPEYSTNAKKLSA 448

  Fly   436 SYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSVVALSLLL 491
            ..::::.....:|:.:...:|.:....|....:.|||...:::||::|:|.|:..:
Worm   449 MLSDQVARKPYSALRYSLKLATSPKPSLFTLKSQHLSFLEFHNLDIFSIVLLTAFI 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	123/478 (26%)
ugt-60	NP_001021158.1	Glycosyltransferase_GTB_type	17..>161	CDD:299143	30/146 (21%)
ugt-60	NP_001021158.1	egt	<253..464	CDD:223071	63/210 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910